Inflammatory Bowel Disease

1. Front Matter

   Pages i-xv

   PDF

2. The Laboratory Bench

   1. Front Matter

      Pages 1-1

      PDF

   2. Introduction: Inflammatory bowel disease: from bench to bedside

      • Fergus Shanahan, Loren C. Karp, Stephan R. Targan

      Pages 3-4

   3. The changing faces of Crohn’s disease and ulcerative colitis

      • Anders Ekbom

      Pages 5-20

   4. Genetics of inflammatory bowel disease

      • Kent D. Taylor, Jerome I. Rotter, Huiying Yang

      Pages 21-65

   5. Experimental mouse models of inflammatory bowel disease: new insights into pathogenic mechanisms

      • Charles O. Elson, Casey T. Weaver

      Pages 67-99

   6. The normal intestinal mucosa: a state of ‘controlled inflammation’

      • Claudio Fiocchi

      Pages 101-120

   7. The lymphocyte-epithelial-bacterial interface

      • Robert Hershberg, Richard S. Blumberg

      Pages 121-146

   8. The mucosal inflammatory response. Cytokines and chemokines

      • Fabio Cominelli, Kristen O. Arseneau, Theresa T. Pizarro

      Pages 147-176

   9. Role of the microcirculation in chronic gut inflammation

      • Matthew B. Grisham, F. Stephen Laroux, D. Neil Granger

      Pages 177-196

   10. Remission, relapse, intestinal healing and repair

       • Michael N. Göke, Daniel K. Podolsky

       Pages 197-209

   11. Antibodies in the exploration of inflammatory bowel disease pathogenesis and disease stratification

       • Jonathan Braun, Offer Cohavy, Mark Eggena

       Pages 211-222

   12. Pathophysiology of inflammatory bowel disease: the effect of inflammation on intestinal function

       • Stephen M. Collins, Kenneth Croitoru

       Pages 223-234

   13. Systemic consequences of intestinal inflammation

       • Konstantinos A. Papadakis, Maria T. Abreu

       Pages 235-250

3. The Bedside

   1. Front Matter

      Pages 251-251

      PDF

   2. Understanding symptoms and signs in inflammatory bowel disease

      • Cornelius C. Cronin, Fergus Shanahan

      Pages 253-267

   3. Clinical course and complications of ulcerative colitis and ulcerative proctitis

      • Remo Panaccione, Lloyd R. Sutherland

      Pages 269-290

   4. Clinical features and complications of Crohn’s disease

      • William J. Tremaine

      Pages 291-304

   5. Mechanisms of systemic inflammation associated with intestinal injury

      • R. Balfour Sartor, Steven N. Lichtman

      Pages 305-335

   6. Pathology of inflammatory bowel disease: a critical appraisal in diagnosis and management

      • Galen Cortina, Klaus Lewin

      Pages 337-355

Inflammatory Bowel Disease: From Bench to Bedside is a detailed and comprehensive story of the local and systemic pathophysiology of intestinal inflammation including management strategies. Research advances and current concepts of etiopathogenesis in the context of what is already known of the clinicopathologic features of these disorders are explored. This volume blends recent advances in the basic and clinical sciences as they relate to inflammatory bowel disease and emphasizes the effectiveness of a team approach of basic scientists and clinician investigators in this field.

• Chemokine
• Colon
• endoscopy
• imaging
• metabolism
• pathophysiology
• physiology

`This is one of the most comprehensive, well written and convincing books on IBD we have had the opportunity to examine in recent years. It is well written (it includes several well known experts in the field), nicely illustrated, up to date (references reach up to 2001) and extremely stimulating. If you have EUR 200 to invest, do not hesitate to buy this book: you will be well rewarded by all you will learn when you glance through its pages.'
Digestive and Liver Disease, 36 (2004)

• Cedars-Sinai IBD Center, Los Angeles, USA

  Stephan R. Targan, Loren C. Karp

• Cork University Hospital, Cork, Ireland

  Fergus Shanahan

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