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Calorie Restriction, Aging and Longevity

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  • © 2010

Overview

  • Discusses how the long-term reduction in calorie or food intake will delay the onset of age-related diseases
  • Provides the latest information on health and life-span effects of Calorie Restriction
  • Covers effects on the molecular, cellular and whole organism level
  • Edited by a team of highly distinguished academics

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Table of contents (18 chapters)

  1. Calorie Restriction in Different Species

  2. Biochemical and Metabolic Mechanisms of Calorie Restriction

  3. Calorie Restriction in the Clinical Setting

Keywords

About this book

Food or calorie restriction has been shown in many short-lived animals and the rhesus monkey to prolong life-span. Life-long nutrition studies are not possible in humans because of their long survival. Studies over two to six years in healthy adult humans have, however, shown that a 20% reduction in food or calorie intake slows many indices of normal and disease-related aging. Thus, it is widely believed that long-term reduction in calorie or food intake will delay the onset of age-related diseases such as heart disease, diabetes and cancer, and so prolong life.

Over the last 20 or more years there has been a progressive rise in food intake in many countries of the world, accompanied by a rising incidence of obesity. Thus our increasing food and calorie intake has been linked to the rising incidence of cardiovascular disease and diabetes in early adult life. It is accepted that overeating, accompanied by reduced physical exercise, will lead to more age-related diseases and shortening of life-span. The answer is to reduce our calorie intake, improve our diet, and exercise more. But calorie restriction is extremely difficult to maintain for long periods. How then can we solve this problem?

Edited by a team of highly distinguished academics, this book provides the latest information on the beneficial effects of calorie restriction on health and life-span. This book brings us closer to an understanding at the molecular, cellular and whole organism level of the way forward.

Editors and Affiliations

  • Sydney, Australia

    Arthur V. Everitt, David G. Couteur

  • University of Aarhus, Aarhus, Denmark

    Suresh I. S. Rattan

  • National Institute on Aging, Gerontology Research Center, National Institute of Health, Baltimore, USA

    Rafael Cabo

Bibliographic Information

  • Book Title: Calorie Restriction, Aging and Longevity

  • Editors: Arthur V. Everitt, Suresh I. S. Rattan, David G. Couteur, Rafael Cabo

  • DOI: https://doi.org/10.1007/978-90-481-8556-6

  • Publisher: Springer Dordrecht

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media B.V. 2010

  • Hardcover ISBN: 978-90-481-8555-9Published: 11 May 2010

  • Softcover ISBN: 978-94-007-9115-2Published: 28 October 2014

  • eBook ISBN: 978-90-481-8556-6Published: 14 June 2010

  • Edition Number: 1

  • Number of Pages: XVI, 323

  • Topics: Human Physiology, Geriatrics/Gerontology, Oxidative Stress

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