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  • Conference proceedings
  • © 2013

Chembiomolecular Science

At the Frontier of Chemistry and Biology

  • Elucidates new biological mechanisms as potential drug targets

  • Provides new insights from the frontiers of research in biology and chemistry

  • Promotes development of new drug therapies to improve human health

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Table of contents (31 papers)

  1. Front Matter

    Pages i-xvi
  2. Chembiomolecular Chemistry

    1. Front Matter

      Pages 1-1
    2. An Approach Toward Identification of Target Proteins of Maitotoxin Based on Organic Synthesis

      • Tohru Oishi, Keiichi Konoki, Rie Tamate, Kohei Torikai, Futoshi Hasegawa, Takeharu Nakashima et al.
      Pages 23-35
    3. Inhibitors of Fatty Acid Amide Hydrolase

      • Dale L. Boger
      Pages 37-49
    4. Toward the Discovery of Small Molecules Affecting RNA Function

      • Shiori Umemoto, Changfeng Hong, Jinhua Zhang, Takeo Fukuzumi, Asako Murata, Masaki Hagihara et al.
      Pages 59-67
    5. The Deep Oceans as a Source for New Treatments for Cancer

      • William Fenical, James J. La Clair, Chambers C. Hughes, Paul R. Jensen, Susana P. Gaudêncio, John B. MacMillan
      Pages 83-91
    6. Search for New Medicinal Seeds from Marine Organisms

      • Motomasa Kobayashi, Naoyuki Kotoku, Masayoshi Arai
      Pages 93-101
  3. Chembiomolecular Biology

    1. Front Matter

      Pages 113-113
    2. Small Molecule-Induced Proximity

      • Fu-Sen Liang, Gerald R. Crabtree
      Pages 115-126
    3. High-Throughput Screening for Small Molecule Modulators of FGFR2-IIIb Pre-mRNA Splicing

      • Erik S. Anderson, Peter Stoilov, Robert Damoiseaux, Douglas L. Black
      Pages 127-138
    4. Roles for the Stress-Responsive Kinases ASK1 and ASK2 in Tumorigenesis

      • Miki Kamiyama, Takehiro Sato, Kohsuke Takeda, Hidenori Ichijo
      Pages 145-153
    5. Establishment of a Novel System for Studying the Syk Function in B Cells

      • Tomohiro Kurosaki, Clifford A. Lowell
      Pages 177-182

About this book

At the forefront of life sciences today is the emerging discipline of chembiomolecular science. This new term describes the integration of the frontier fields of chemical biology, chemistry, and pharmacology. Chembiomolecular science aims to elucidate new biological mechanisms as potential drug targets and enhance the creation of new drug therapies. This book comprises the proceedings of the Uehara Memorial Foundation Symposium 2011, which focused on the most recent advances in chembiomolecular science made by leading experts in the field. The book is divided into three main topics. The first is the chemical approach to understanding complex biological systems on a molecular level using chemical compounds as a probe. The second describes the biological approach used to develop new lead drug compounds. The third focuses on the biological system that serves as the potential drug target, the beginning step in the process of developing new drugs. Replete with the latest research, the book will draw the attention of all scientists interested in the synergies between chemistry and biology to elucidate life on a molecular level and to promote drug discovery. Ultimately, the book helps promote the understanding of biological functions at the molecular level and create new pharmaceuticals that can contribute to improving human health.

Editors and Affiliations

  • Institute of Microbial Chemistry, Tokyo, Japan

    Masakatsu Shibasaki

  • The University of Tokyo, Department of Pharmacology, Graduate School of Medicine, Bunkyo-ku, Japan

    Masamitsu Iino

  • RIKEN Advanced Science Institute, Antibiotics Laboratory, Chemical Biology Core Facility, Wako, Japan

    Hiroyuki Osada

Bibliographic Information

  • Book Title: Chembiomolecular Science

  • Book Subtitle: At the Frontier of Chemistry and Biology

  • Editors: Masakatsu Shibasaki, Masamitsu Iino, Hiroyuki Osada

  • DOI: https://doi.org/10.1007/978-4-431-54038-0

  • Publisher: Springer Tokyo

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Japan 2013

  • Hardcover ISBN: 978-4-431-54037-3Published: 03 October 2012

  • Softcover ISBN: 978-4-431-56326-6Published: 23 August 2016

  • eBook ISBN: 978-4-431-54038-0Published: 02 October 2012

  • Edition Number: 1

  • Number of Pages: XVI, 325

  • Topics: Biochemistry, general, Cell Biology, Molecular Medicine

Buy it now

Buying options

eBook USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access