Overview
- Summarizes the most advanced technical aspects from sample generation to data analysis
- Presents successful applications of microarrays in major fields of inflammation research
- Helps to plan, perform and analyse microarray experiments
Part of the book series: Progress in Inflammation Research (PIR)
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Table of contents (17 chapters)
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Front Matter
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Microarray and inflammation: An introduction
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Methods and protocols for the generation of gene expression profiles in inflammation research
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Front Matter
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Single and rare cell analysis — amplification methods
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Selected applications of microarrays in inflammation research
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Front Matter
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Cross-platform microarray analysis
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A regulatory perspective
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Outlook
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Front Matter
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Keywords
About this book
The book is of interest to academic and industrial researchers but also clinicians who are working on inflammation related topics and would like to extend their knowledge about microarrays and the application thereof. After reading the book a researcher or clinician should be in the position to plan, perform and analyse or to critically review microarray experiments related to inflammation research.
So far, non of the published books covers all aspects which need to be taken into account when planning and performing a microrray experiment in inflammation research. Normally, for a researcher or clinician doing a microarray experiment it is not enough to have knowledge about microarrays , as the experiment does not start with purified and quality controlled RNA and does not end with signal intensities. Things like appropriate cell sorting techniques, stabilisation and transport of RNA or cells, the knowledge how to deal with whole blood as well as options for automation are crucial for a successful application of microarrays. Moreover these aspects are the main obstacles for transferring microarray based inflammation analysis from bench to bedside and the limiting factors for higher through put as needed in multicenter studies.
Editors and Affiliations
Bibliographic Information
Book Title: Microarrays in Inflammation
Editors: Andreas Bosio, Bernhard Gerstmayer
Series Title: Progress in Inflammation Research
DOI: https://doi.org/10.1007/978-3-7643-8334-3
Publisher: Birkhäuser Basel
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Birkhäuser Basel 2008
Hardcover ISBN: 978-3-7643-8333-6Published: 20 October 2008
eBook ISBN: 978-3-7643-8334-3Published: 14 May 2009
Series ISSN: 1422-7746
Series E-ISSN: 2296-4525
Edition Number: 1
Number of Pages: XI, 232
Number of Illustrations: 25 b/w illustrations, 2 illustrations in colour
Topics: Microarrays, Immunology, Cell Biology, Hematology, Biotechnology, Pharmacology/Toxicology