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Prostate Cancer Prevention

  • Book
  • © 2014

Overview

Editors:
  1. Jack Cuzick

    1. Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine Queen Mary University of London, London, United Kingdom

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  2. Mangesh A. Thorat

    1. Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine Queen Mary University of London, London, United Kingdom

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Wide-ranging coverage of recent evidence on the prevention of prostate cancer, of interest for both clinicians and researchers
  • Detailed discussion of risk prediction biomarkers
  • Evaluation of the potential role of various means of chemoprevention
  • Includes supplementary material: sn.pub/extras

Part of the book series: Recent Results in Cancer Research (RECENTCANCER, volume 202)

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Table of contents (18 chapters)

  1. Front Matter

    Pages i-viii
    Download chapter PDF

  2. The Biology and Natural History of Prostate Cancer: A Short Introduction

    • Lars Holmberg, Mieke Van Hemelrijck
    Pages 1-7

  3. Germline Genetic Variants Associated with Prostate Cancer and Potential Relevance to Clinical Practice

    • Chee Leng Goh, Rosalind Anne Eeles
    Pages 9-26

  4. Lifestyle and Dietary Factors in Prostate Cancer Prevention

    • Andrea Discacciati, Alicja Wolk
    Pages 27-37

  5. Nutrition, Hormones and Prostate Cancer Risk: Results from the European Prospective Investigation into Cancer and Nutrition

    • Timothy J. Key
    Pages 39-46

  6. Screening for Prostate Cancer: Current Status of ERSPC and Screening-Related Issues

    • Fritz H. Schröder
    Pages 47-51

  7. Update of the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial

    • Gerald L. Andriole
    Pages 53-57

  8. ERSPC, PLCO Studies and Critique of Cochrane Review 2013

    • Fritz H. Schröder
    Pages 59-63

  9. Screening for Prostate Cancer: Reflecting on the Quality of Evidence from the ERSPC and PLCO Studies

    • Dragan Ilic
    Pages 65-71

  10. Phase III Prostate Cancer Chemoprevention Trials

    • Howard L. Parnes, Otis W. Brawley, Lori M. Minasian, Leslie G. Ford
    Pages 73-77

  11. Risk Adapted Chemoprevention for Prostate Cancer: An Option?

    • Bernd J. Schmitz-Dräger, Oliver Schöffski, Michael Marberger, Sevim Sahin, Hans-Peter Schmid
    Pages 79-91

  12. Aspirin and Prostate Cancer Prevention

    • Cristina Bosetti, Valentina Rosato, Silvano Gallus, Carlo La Vecchia
    Pages 93-100

  13. Chemoprevention of Prostate Cancer by Isoflavonoids

    • Stefan Aufderklamm, Florian Miller, Anastasia Galasso, Arnulf Stenzl, Georgios Gakis
    Pages 101-108

  14. Lycopene for the Prevention and Treatment of Prostate Disease

    • Dragan Ilic
    Pages 109-114

  15. Chemoprevention of Prostate Cancer with the Polyamine Synthesis Inhibitor Difluoromethylornithine

    • Frank L. Meyskens Jr., Anne R. Simoneau, Eugene W. Gerner
    Pages 115-120

  16. Prostate Cancer Prevention: Agent Development Strategies

    • Howard L. Parnes, Margaret G. House, Joseph A. Tangrea
    Pages 121-131

  17. Prognostic Value of a Cell Cycle Progression Score for Men with Prostate Cancer

    • Jack Cuzick
    Pages 133-140

  18. Distinguishing Indolent from Aggressive Prostate Cancer

    • Zoran Culig
    Pages 141-147

  19. Management of Low Risk and Low PSA Prostate Cancer: Long Term Results from the Prostate Cancer Intervention Versus Observation Trial

    • Timothy J. Wilt
    Pages 149-169
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Keywords

About this book

Prostate cancer is by far the most common cancer in men and the second leading cause of death due to cancer. It comprises a mixed group of tumours displaying varying clinical behaviour: while some have a very aggressive course, others are rather indolent. Prevention of prostate cancer and discrimination between aggressive and indolent forms are important clinical goals and the acquisition of significant new evidence on means of achieving these aims makes this book particularly timely. A wide range of topics are covered by leading authorities in the field. The biology and natural history of prostate cancer are reviewed and the role of lifestyle and dietary factors, assessed. Detailed attention is paid to risk prediction biomarkers and to the role of novel high-throughput nucleic acid-based technologies in improving risk prediction and thereby allowing tailored approaches to cancer prevention. Potential means of chemoprevention of prostate cancer are also reviewed in depth, covering the very positive new data on the impact of aspirin as well as evidence regarding 5α-reductase inhibitors, DFMO and lycopene. Guidance is provided on the differentiation of aggressive from indolent disease and the policy and research implications of recent findings are examined. This book will be of interest to both clinicians and researchers.

Reviews

From the reviews:

“Part of the Recent Advances in Cancer Research series, this book’s title suggests that it tackles prevention of prostate cancer. … scientists and clinicians who deal with prostate cancer are the main audience. … The discussion of agent development and strategies is very useful to anyone looking to tackle the challenging area of prostate cancer chemoprevention.” (Leonard G. Gomella, Doody’s Book Reviews, May, 2014)

Editors and Affiliations

  • Centre for Cancer Prevention, Wolfson Institute of Preventive Medicine Queen Mary University of London, London, United Kingdom

    Jack Cuzick, Mangesh A. Thorat

Bibliographic Information

  • Book Title: Prostate Cancer Prevention

  • Editors: Jack Cuzick, Mangesh A. Thorat

  • Series Title: Recent Results in Cancer Research

  • DOI: https://doi.org/10.1007/978-3-642-45195-9

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2014

  • Hardcover ISBN: 978-3-642-45194-2Published: 03 March 2014

  • Softcover ISBN: 978-3-662-52443-5Published: 03 September 2016

  • eBook ISBN: 978-3-642-45195-9Published: 15 February 2014

  • Series ISSN: 0080-0015

  • Series E-ISSN: 2197-6767

  • Edition Number: 1

  • Number of Pages: VIII, 169

  • Number of Illustrations: 7 b/w illustrations, 4 illustrations in colour

  • Topics: Oncology, Urology, Cancer Research

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