Skip to main content
SpringerLink
Log in
Book cover

Microarrays in Diagnostics and Biomarker Development

Current and Future Applications

  • Book
  • © 2012

Overview

Editors:
  1. Bertrand Jordan

    1. CNRS, La Cadière d’Azur, France

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Up-to-date overview of microarray applications

  • For scientists, but also useful for clinicians and technology developers

  • The editor is the founder and coordinator of the Marseille-Nice Genopole genomics consortium

  • Includes supplementary material: sn.pub/extras

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (13 chapters)

  1. Front Matter

    Pages i-viii
    Download chapter PDF

  2. The Microarray Paradigm and Its Various Implementations

    • Bertrand Jordan
    Pages 1-8

  3. DNA Arrays

    1. Front Matter

      Pages 9-9
      Download chapter PDF

    2. DNA Arrays in Many Guises

      • Bertrand Jordan
      Pages 11-19

    3. Expression Profiling for Diagnostics

      • Bertrand Jordan
      Pages 21-27

    4. Genotype Characterisation for Diagnostics

      • Bertrand Jordan
      Pages 29-38

    5. Array-CGH and SNP-Arrays, the New Karyotype

      • Karoly Szuhai
      Pages 39-52

  4. Protein (Antigen and Antibody) and Peptide Arrays

    1. Front Matter

      Pages 53-53
      Download chapter PDF

  5. Protein (Antigen & Antibody) and Peptide Arrays

    1. Protein Microarrays and Their Potential Clinical Applications in the Era of Personalized Medicine

      • Hong Zhang, Steven Pelech
      Pages 55-80

    2. Peptide Arrays

      • Hong Zhang, Steven Pelech, Rob Ruijtenbeek, Thomas Felgenhauer, Ralf Bischoff, Frank Breitling et al.
      Pages 81-112

    3. Slow Off-Rate Modified Aptamer Arrays for Biomarker Discovery and Diagnostic Applications

      • Jeffrey J. Walker, Edward N. Brody, Larry Gold
      Pages 113-131

  6. Other Types of Arrays

    1. Front Matter

      Pages 133-133
      Download chapter PDF

  7. Other types of arrays

    1. Tissue Microarrays for Translational Research

      • Ronald Simon, Martina Mirlacher
      Pages 135-152

    2. Recent and Future Developments of Microarrays: Miniaturization and Lab-on-Chip Approaches

      • Inbal Tsarfati-BarAd, Levi A. Gheber
      Pages 153-168

  8. Data Analysis, Commercial and Regulatory Aspects

    1. Front Matter

      Pages 169-169
      Download chapter PDF

  9. Data analysis, commercial and regulatory aspects

    1. Analysis of Array Data and Clinical Validation of Array-Based Assays

      • Benjamin Haibe-Kains, John Quackenbush
      Pages 171-210

    2. Challenges in the Commercialization of Array-Based Tests

      • Justin Petrone
      Pages 211-227

    3. Genes, Microarrays, and Patents

      • Justin Petrone
      Pages 229-236

  10. Back Matter

    Pages 237-240
    Download chapter PDF
Back to top

Keywords

About this book

Microarray technology has made strong progress over the past decade, and there have also been significant changes in application areas, from nucleic acids to proteomics and from research to clinical applications. This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. The focus is on entities that are in actual clinical use, or quite close, and on recent developments, such as peptide and aptamer arrays. A further topic is the miniaturisation towards “nanoarrays”, which is expected to have great potential in clinical applications. Relevant issues of bioinformatics and statistical analysis of array data are discussed in detail, as well as the barriers to the commercialisation of array-based tests and the vexing IP issues involved. Thus, the book should be very useful tor active array users as well as to newcomers seeking to make the best choice between different technologies.

Editors and Affiliations

  • CNRS, La Cadière d’Azur, France

    Bertrand Jordan

Bibliographic Information

  • Book Title: Microarrays in Diagnostics and Biomarker Development

  • Book Subtitle: Current and Future Applications

  • Editors: Bertrand Jordan

  • DOI: https://doi.org/10.1007/978-3-642-28203-4

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2012

  • Hardcover ISBN: 978-3-642-28202-7Published: 21 April 2012

  • Softcover ISBN: 978-3-642-43976-6Published: 09 May 2014

  • eBook ISBN: 978-3-642-28203-4Published: 23 April 2012

  • Edition Number: 1

  • Number of Pages: VIII, 240

  • Topics: Microarrays, Cell Biology

Publish with us

Policies and ethics

Back to top

Search

Navigation