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Retinal Degenerative Diseases

  • Conference proceedings
  • © 2012

Overview

Editors:
  1. Matthew M. LaVail

    1. University of California, San Francisco, San Francisco, USA

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  2. John D. Ash

    1. University of Oklahoma Health Sciences C, Oklahoma City, USA

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  3. Robert E. Anderson

    1. Health Science Center, Dean A. McGee Eye Inst., University of Oklahoma, OKLAHOMA CITY, USA

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  4. Joe G. Hollyfield

    1. Division of Ophthalmology, Cole Eye Institute at the Cleveland Clin, Cleveland, USA

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  5. Christian Grimm

    1. Experimental Ophthalmology, University of Zurich, ZURICH, Switzerland

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  • Focus on new developments
  • Includes new topics in the field not covered in previous years
  • Will represent state-of-the-art research
  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 723)

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Table of contents (108 papers)

  1. Front Matter

    Pages i-lxiv
    Download chapter PDF

  2. AMD: Basic Mechanisms, Inflammation and Immunity

    1. Front Matter

      Pages 1-1
      Download chapter PDF

    2. A Window to Innate Neuroimmunity: Toll-Like Receptor-Mediated Cell Responses in the Retina

      • Mark E. Kleinman, Jayakrishna Ambati
      Pages 3-9

    3. Autoimmune Biomarkers in Age-Related Macular Degeneration: A Possible Role Player in Disease Development and Progression

      • Alessandro Iannaccone, Indira Neeli, Pratheebha Krishnamurthy, Nataliya I. Lenchik, Haibao Wan, Ivan C. Gerling et al.
      Pages 11-16

    4. Local Vs. Systemic Mononuclear Phagocytes in Age-Related Macular Degeneration and Their Regulation by CCL2–CCR2 and CX3CL1–CX3CR1 Chemokine Signalling

      • Ulrich F. O. Luhmann, Robin R. Ali
      Pages 17-22

    5. Sublytic Membrane-Attack-Complex Activation and VEGF Secretion in Retinal Pigment Epithelial Cells

      • Kannan Kunchithapautham, Mausumi Bandyopadhyay, Mohammad Dahrouj, Joshua M. Thurman, Bärbel Rohrer
      Pages 23-30

    6. Complement Activation in Retinal Degeneration

      • Matt Rutar, Riccardo Natoli, Jan Provis, Krisztina Valter
      Pages 31-36

    7. Microglia in the Outer Retina and Their Relevance to Pathogenesis of Age-Related Macular Degeneration

      • Wenxin Ma, Lian Zhao, Wai T. Wong
      Pages 37-42

    8. Lutein or Zeaxanthin Supplementation Suppresses Inflammatory Responses in Retinal Pigment Epithelial Cells and Macrophages

      • Qingning Bian, Tingyu Qin, Zhihong Ren, Dayong Wu, Fu Shang
      Pages 43-50

    9. Exploring the Potential Role of the Oxidant-Activated Transcription Factor Aryl Hydrocarbon Receptor in the Pathogenesis of AMD

      • Goldis Malek, Mary Dwyer, Donald McDonnell
      Pages 51-59

    10. Common Mechanisms for Separate Maculopathies?

      • Elod Kortvely, Marius Ueffing
      Pages 61-66

    11. The Role of Amyloid-β in Retinal Degeneration

      • Julien Bruban, Virginie Dinet, Frédéric Mascarelli
      Pages 67-74

    12. Molecule-Specific Imaging and Quantitation of A2E in the RPE

      • Zsolt Ablonczy, Danielle B. Gutierrez, Angus C. Grey, Kevin L. Schey, Rosalie K. Crouch
      Pages 75-81

    13. Autophagy in the Retina: A Potential Role in Age-Related Macular Degeneration

      • Sayak K. Mitter, Haripriya Vittal Rao, Xiaoping Qi, Jun Cai, Andrew Sugrue, William A. Dunn Jr. et al.
      Pages 83-90

  3. Neuroprotection, Drugs and Novel Protective Therapies

    1. Front Matter

      Pages 91-91
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    2. Regeneration of Cone Outer Segments Induced by CNTF

      • Rong Wen, Weng Tao, Lingyu Luo, Deqiang Huang, Konrad Kauper, Paul Stabila et al.
      Pages 93-99

    3. Glucocorticoid-Dependent Mechanisms in Photoreceptor Survival

      • Marisa A. Cubilla, Mauricio M. Castañeda, Tomás P. Bachor, Angela M. Suburo
      Pages 101-106

    4. HDAC Inhibition Prevents Rd1 Mouse Photoreceptor Degeneration

      • Javier Sancho-Pelluz, François Paquet-Durand
      Pages 107-113

    5. Neuroprotective Dose Response in RCS Rats Implanted with Microphotodiode Arrays

      • Machelle T. Pardue, Moon K. Kim, Tiffany A. Walker, Amanda E. Faulkner, Alan Y. Chow, Vincent T. Ciavatta
      Pages 115-120

    6. Treatment with 670-nm Light Protects the Cone Photoreceptors from White Light-Induced Degeneration

      • Rizalyn S. Albarracin, Krisztina Valter
      Pages 121-128
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Keywords

About this book

This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.

Editors and Affiliations

  • University of California, San Francisco, San Francisco, USA

    Matthew M. LaVail

  • University of Oklahoma Health Sciences C, Oklahoma City, USA

    John D. Ash

  • Health Science Center, Dean A. McGee Eye Inst., University of Oklahoma, OKLAHOMA CITY, USA

    Robert E. Anderson

  • Division of Ophthalmology, Cole Eye Institute at the Cleveland Clin, Cleveland, USA

    Joe G. Hollyfield

  • Experimental Ophthalmology, University of Zurich, ZURICH, Switzerland

    Christian Grimm

Bibliographic Information

  • Book Title: Retinal Degenerative Diseases

  • Editors: Matthew M. LaVail, John D. Ash, Robert E. Anderson, Joe G. Hollyfield, Christian Grimm

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-1-4614-0631-0

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2012

  • Hardcover ISBN: 978-1-4614-0630-3Published: 21 December 2011

  • Softcover ISBN: 978-1-4939-4173-5Published: 23 August 2016

  • eBook ISBN: 978-1-4614-0631-0Published: 21 December 2011

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: LXIV, 864

  • Topics: Immunology, Ophthalmology, Geriatrics/Gerontology, Gene Therapy

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