Fluprazine hydrochloride decreases play behavior but not social grooming in juvenile male rats
Treatment with 8 mg/kg fluprazine hydrochloride strongly inhibited the play behavior of juvenile male rats but had no effect on social grooming. The results indicate that fluprazine affects play behavior as well as conspecific and predatory attack, male copulation, and maternal behavior. These drug actions may result from a rather generalized disruption in higher order stimulus processing or a drug-induced potentiation of fearfulness.
- Bean, N. J. (1982). Modulation of agonistic behavior by the dual olfactory system in male mice. Physiology & Behavior, 29, 433–437. CrossRef
- Blanchard, D. C., Takushi, R., Blanchard, R. J., Flannelly, K. J., & Kemble, E. D. (1985). Fluprazine hydrochloride does not decrease defensive behaviors of wild and septal syndrome rats. Physiology & Behavior, 35, 349–353. CrossRef
- Bradford, L. D., Olivier, B., van Dalen, D., & Schipper, J. (1984). Serenics: The pharmacology of fluprazine and DU 28412. In K. A. Miczek, M. R. Kruk, & B. Olivier (Eds.), Ethnopharmacological aggression research (pp. 191–207). New York: Liss.
- Bronson, F. H. (1974). Pheromonal influences on reproductive activities in rodents. In M. C. Birch (Ed.), Pheromones (pp. 344–365). New York: American Elsevier.
- Fagen, R. (1981). Animal play behavior. New York: Oxford University Press.
- Flannelly, K. J., Lim, H., Diamond, M., Blanchard, D. C., & Blanchard, R. J. (1985). Fluprazine hydrochloride decreases copulation in male rats. Pharmacology, Biochemistry & Behavior, 22, 1–4. CrossRef
- Flannelly, K. J., Muraoka, M. Y., Blanchard, D. C., & Blanchard, R. J. (1985). Specific anti-aggressive effects of fluprazine hydrochloride. Psychopharmacology, 87, 86–89. CrossRef
- Kemble, E. D., & Schultz, L. A. (in press). Effects of fluprazine hydrochloride on maternal behavior in mice. Behavioural Processes.
- Kemble, E. D., Thornton, A. E., & Schultz, L. A. (1987). Some fear-potentiating effects of fluprazine hydrochloride in mice. Aggressive Behavior, 13, 269–280. CrossRef
- Meany, M. J., & Stewart, J. (1981). A descriptive study of social development in the rat. (Rattus norvegicus). Animal Behavior, 29, 34–45. CrossRef
- Murphy, M. R., & Schneider, G. E. (1970). Olfactory bulb removal eliminates mating behavior in the male golden hamster. Science, 167, 302–304. CrossRef
- Olivier, B., Mos, J., van der Poel, A. M., Krijzer, F. N. C., & Kruk, M. R. (1984). Effects of a new psychoactive drug (DU27716) on different models of rat agonistic behaviour and EEG. In K. J. Flannelly, R. J. Blanchard, & D. C. Blanchard (Eds.), Biological perspectives on aggression (pp. 261–279). New York: Liss.
- Panksepp, J., & Beatty, W. W. (1980). Social deprivation and play in rats. Behavioral & Neural Biology, 30, 197–206. CrossRef
- Pellis, S. M., & Pellis, V. C. (1987). Play-fighting differs from serious fighting in both target of attack and tactics of fighting in the laboratory rat (Rattus norvegicus). Aggressive Behavior, 13, 227–242. CrossRef
- Racine, M. A., Flannelly, K. J., & Blanchard, D. C. (1984). Anti-aggressive effects of DU 27716 on attack and defensive behaviors in male mice. In K. J. Flannelly, R. J. Blanchard, & D. C. Blanchard (Eds.), Biological perspectives on aggression (pp. 281–294). New York: Liss.
- Schultz, L. A., & Kemble, E. D. (1986). Prey-dependent effects of fluprazine hydrochloride on predatory aggression in northern grasshopper mice (Onychomys leucogaster) and rats (Rattus norvegicus). Aggressive Behavior, 12, 267–275. CrossRef
- Thor, D. H., & Holloway, W. R. (1982). Anosmia and play fighting behavior in prepubescent male and female rats. Physiology & Behavior, 29, 281–285. CrossRef
- Fluprazine hydrochloride decreases play behavior but not social grooming in juvenile male rats
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Volume 26, Issue 6 , pp 563-564
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