Location preference and flavor aversion reinforced by amphetamine in rats
- Cite this article as:
- Reicher, M.A. & Holman, E.W. Animal Learning & Behavior (1977) 5: 343. doi:10.3758/BF03209576
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To associate the identical drug state with both a location and a flavor, rats were given intraperitoneal amphetamine injections and then confined for 20 min in one side of a shuttlebox with access to a flavored solution; on control trials without injections, they were confined for 20 min in the opposite side with a different flavor. In the first experiment, the rats were placed in the shuttlebox immediately after injections; in the second experiment, they were placed in the shuttlebox 20 min after injections. Subsequent free-choice tests in both experiments revealed an increased choice of the side of the shuttlebox associated with amphetamine but also an aversion to the flavored solution associated with the drug.