Abstract
Comparative analysis of rhamnose-positive Y. pestis strains, which are traditionally recognized as the biovar altaica, was performed with the use of molecular typing. The strains were isolated from the natural plague foci of the Changay mountainous system and the Sailugem natural plague focus in Mongolia. The Russian part of the latter is known as the Altai Mountains focus (focus 36). All isolates were compared with the other rhamnose-positive vole strains from the natural plague foci located in the grassland of Xilingol (focus L, China), the plateau of Qinghai-Tibet (focus M, China), the Gissarian Ridge (focus 34, Tadjikistan and Uzbekistan), and the Talassian Ridge (focus 40, Kyrgyzstan). The strains studied formed a single cluster with two branches, of which the first branch included the talassica (0.PE4?), qinghaiensis (0.PE4ab), and xilingolensis (0.PE4cd) phylogenetic groups, while the second included the hissarica (0.PE9) and altaica (0.PE1) phylogenetic groups. The results of molecular typing suggest that several strains from the Qinghai group of the Mongolian foci belong to the qinghaiensis and xilingolensis biovars but not to the altaica biovar.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Ad’yasuren, Z., Tserennorov, D., Otgonbaatar, D., Balakhonov, S.V., Innokentyeva, T.I., Agiimaa, Sh., et al., Clinical-epidemiological features of plague in Mongolia, Probl. Osobo Opasn. Infekts., 2010, vol. 103, pp. 30–33.
Balakhonov, S.V., Tséndzhav, S., and Erdénébat, A., New plasmidovars of Yersinia pestis isolated in Mongolia, Mol. Genet. Microbiol. Virusol., 1991, vol. 11, pp. 27–29.
Goncharov, A.I., Tokhov, Yu.M., Plotnikova, E.P., and Artyushina, Yu.S., List of Species and Subspecies of Fleas Infected by Yersinia pestis in Nature, Stavropol: RIO IDNK Publ., 2013.
Platonov, M.E., Evseeva, V.V., Efremenko, D.V., Kuznetsova, I.V., Chirkova, E.V., Dentovskaya, S.V., et al., DFR-typing of Yersinia pestis strains from the CIS natural foci, Probl. Osobo Opasn. Infekts., 2011, vol. 108, pp. 42–45.
Natural Plague Foci in the Caucasus, Caspian Sea Region, Central Asia, and Siberia, Onishchenko, G.G. and Kutyrev, V.V., Eds., Moscow: Meditsina, 2004.
Anisimov, A.P., Dentovskaya, S.V., Panfertsev, E.A., Svetoch, T.E., Kopylov, P.Kh., Segelke, B.W., et al., Amino acid and structural variability of Yersinia pestis LcrV protein, Infect. Genet. Evol., 2010, vol. 10, no. 1, pp. 137–145.
Anisimov, A.P., Lindler, L.E., and Pier, G.B., Intraspecific diversity of Yersinia pestis, Clin. Microbiol. Rev., 2004, vol. 17, no. 2, pp. 434–464.
Bearden, S.W., Sexton, C., Pare, J., Fowler, J.M., Arvidson, C.G., Yerman, L., et al., Attenuated enzootic (pestoides) isolates of Yersinia pestis express active aspartase, Microbiology, 2009, vol. 155, no. 1, pp. 198–209.
Cui, Y., Li, Y., Gorgé, O., Platonov, M.E., Yan, Y., Guo, Z., et al., Insight into microevolution of Yersinia pestis by clustered regularly interspaced short palindromic repeats, PLoS One, 2008, vol. 3, no. 7, p. e2652.
Cui, Y., Yu, C., Yan, Y., Li, D., Li, Y., Jombart, T., et al., Historical variations in mutation rate in an epidemic pathogen, Yersinia pestis, Proc. Natl. Acad. Sci. U. S. A., 2013, vol. 110, no. 2, pp. 577–582.
Kiefer, D., Dalantai, G., Damdindorj, T., Riehm, J.M., Tomaso, H., Zöller, L., et al., Phenotypical characterization of Mongolian Yersinia pestis strains, Vector Borne Zoonotic. Dis., 2012, vol. 12, no. 2, pp. 183–188.
Li, Y., Cui, Y., Hauck, Y., Platonov, M.E., Dai, E., Song, Y., et al., Genotyping and phylogenetic analysis of Yersinia pestis by MLVA: insights into the worldwide expansion of Central Asia plague foci, PLoS One, 2009, vol. 4, no. 6, p. e6000.
Li, Y., Dai, E., Cui, Y., Li, M., Zhang, Y., Wu, M., et al., Different region analysis for genotyping Yersinia pestis isolates from China, PLoS One, 2008, vol. 3, no. 5, p. e2166.
Morelli, G., Song, Y., Mazzoni, C.J., Eppinger, M., Roumagnac, P., Wagner, D.M., et al., Yersinia pestis genome sequencing identifies patterns of global phylogenetic diversity, Nat. Genet., 2010, vol. 42, no. 12, pp. 1140–1143.
Platonov, M.E., Evseeva, V.V., Dentovskaya, S.V., and Anisimov, A.P., Molecular typing of Yersinia pestis, Mol. Genet. Microbiol. Virusol., 2013, vol. 28, no. 2, pp. 41–51.
Platonov, M.E., Evseeva, V.V., Svetoch, T.E., Efremenko, D.V., Kuznetsova, I.V., Dentovskaya, S.V., et al., Phylogeography of Yersinia pestis vole strains isolated from natural foci of the Caucasus and South Caucasus, Mol. Genet. Microbiol. Virusol., 2012, vol. 27, no. 3, pp. 108–111.
Riehm, J.M., Vergnaud, G., Kiefer, D., Damdindorj, T., Dashdava, O., Khurelsukh, T., et al., Yersinia pestis lineages in Mongolia, PLoS One, 2012, vol. 7, no. 2, p. e30624.
Vavilov, N.I., The law of homologous series in variation, J. Genet., 1922, vol. 12, no. 1, pp. 47–89.
Zhou, D., Han, Y., Song, Y., Huang, P., and Yang, R., Comparative and evolutionary genomics of Yersinia pestis, Microb. Infect., 2004, vol. 6, no. 13, pp. 1226–1234.
Author information
Authors and Affiliations
Corresponding author
Additional information
Original Russian Text © M.E. Platonov, V.V. Evseeva, D.V. Efremenko, M.V. Afanas’ev, D.B. Verzhutski, I.V. Kuznetsova, M.Yu. Shestopalov, S.V. Dentovskaya, A.N. Kulichenko, S.V. Balakhonov, A.P. Anisimov, 2015, published in Molekulyarnaya Genetika, Mikrobiologiya i Virusologiya, 2015, No. 1, pp. 23–28.
About this article
Cite this article
Platonov, M.E., Evseeva, V.V., Efremenko, D.V. et al. Intraspecies classification of rhamnose-positive Yersinia pestis strains from natural plague foci of Mongolia. Mol. Genet. Microbiol. Virol. 30, 24–29 (2015). https://doi.org/10.3103/S0891416815010073
Received:
Published:
Issue Date:
DOI: https://doi.org/10.3103/S0891416815010073