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Analysis of crystal and three dimensional structures of drug substances

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Moscow University Chemistry Bulletin Aims and scope

Abstract

The alteration of a crystalline state or the optical isomerism of a substance significantly affects the physicochemical, pharmacotechnological properties, and bioavailability of drugs. It was shown that X-Ray powder diffraction, infrared Fourier spectroscopy, differential scanning calorimetry, optical microscopy, and circular dichroism methods can be successfully used for the quality control of drug substances.

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Authors and Affiliations

  1. Department of Natural Compound Chemistry, Moscow State University, Moscow, Russia

    I. G. Smirnova, G. N. Gil’deeva & V. V. Chistyakov

Authors
  1. I. G. Smirnova
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  2. G. N. Gil’deeva
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  3. V. V. Chistyakov
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Corresponding author

Correspondence to I. G. Smirnova.

Additional information

Original Russian Text © I.G. Smirnova, G.N. Gil’deeva, V.V. Chistyakov, 2012, published in Vestnik Moskovskogo Universiteta. Khimiya, 2012, No. 4, pp. 234–240.

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Smirnova, I.G., Gil’deeva, G.N. & Chistyakov, V.V. Analysis of crystal and three dimensional structures of drug substances. Moscow Univ. Chem. Bull. 67, 196–201 (2012). https://doi.org/10.3103/S0027131412040116

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  • DOI: https://doi.org/10.3103/S0027131412040116

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