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Simulation of thermal lesions in biological tissues irradiated by high-intensity focused ultrasound through the rib cage

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Abstract

Thermal effect of high-intensity focused ultrasound on biological tissue behind the rib cage phantom has been numerically simulated. A phased array was used as a source of ultrasound. Temperature and thermal dose distributions in the biological tissue were calculated and used to find the form of thermal lesions. The results of the calculations are in good agreement with experiment and show that the model is applicable for predicting the effect produced by ultrasound in tissue.

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References

  1. C. Hill, J. Bamber, and G. ter Haar, Physical Principles of Medical Ultrasonics, 2nd ed. (Wiley, Chichester, 2004).

    Book  Google Scholar 

  2. M. R. Bailey, V. A. Khokhlova, O. A. Sapozhnikov, S. G. Kargl, and L.A. Crum, “Physical Mechanisms of the Therapeutic Effect of Ultrasound (A Review),” Acoust. Phys. 49(4), 369 (2003).

    Article  ADS  Google Scholar 

  3. F. Li, X. Gong, K. Hu, C. Li, and Z. Wang, “Effect of Ribs in HIFU Beam Path on Formation of Coagulative Necrosis in Goat Liver,” in Proceedings of the Therapeutic Ultrasound: 5th International Symposium on Therapeutic Ultrasound (Boston, Massachusetts, 27–29 October 2005). AIP Conf. Proc. 829, 477 (2006).

    Google Scholar 

  4. S. Bobkova, L. Gavrilov, V. Khokhlova, A. Shaw, and J. Hand, “Focusing of High Intensity Ultrasound through the Rib Cage Using Therapeutic Random Phased Array,” Ultrasound in Medicine and Biology. 36(6), 888 (2010).

    Article  Google Scholar 

  5. S. A. Sapareto and W.C. Dewey, “Thermal Dose Determination in Cancer Therapy,” Rad. Oncol. Biol. Phys. 10, 787 (1984).

    Article  Google Scholar 

  6. E. A. Filonenko, L. R. Gavrilov, V. A. Khokhlova, and J.W. Hand, “Heating of Biological Tissues by Two-Dimensional Phased Arrays with Random and Regular Element Distributions,” Acoust. Phys. 50(2), 222 (2004).

    Article  ADS  Google Scholar 

  7. F. A. Duck, Physical Properties of Tissue (Academic Press, London, 1990), p. 346.

    Google Scholar 

  8. J.W. Hand, A. Shaw, N. Sadhoo, S. Rajagopal, R. J. Dickinson, and L.R. Gavrilov, “A Random Phased Array Device for Delivery of High Intensity Focused Ultrasound,” Phys. Med. Biol. 54, 5675 (2009).

    Article  Google Scholar 

  9. L. R. Gavrilov and J.W. Hand, “A Theoretical Assessment of the Relative Performance of Spherical Phased Arrays for Ultrasound Surgery and Therapy,” IEEE Trans. Ultrason. Ferroelec. Freq. Contr. 41(1), 125 (2000).

    Article  Google Scholar 

  10. E. S. Ebbini and C.A. Cain, “Multiple-Focus Ultrasound Phased Array Pattern Synthesis: Optimal Driving Signal Distributions for Hyperthermia,” IEEE Trans. Ultrason. Ferroelec. Freq. Contr. 36(5), 540 (1989).

    Article  Google Scholar 

  11. S. A. Goss, L. A. Frizzell, J. T. Kouzmanoff, J.M. Barich, and J. M. Yang, “Sparse Random Ultrasound Phased Array for Focal Surgery,” IEEE Trans. Ultrason. Ferroelec. Freq. Contr. 43(6), 1111 (1996).

    Article  Google Scholar 

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Correspondence to S. A. Ilyin.

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Ilyin, S.A., Bobkova, S.M., Khokhlova, V.A. et al. Simulation of thermal lesions in biological tissues irradiated by high-intensity focused ultrasound through the rib cage. Phys. Wave Phen. 19, 62–67 (2011). https://doi.org/10.3103/S1541308X11010122

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  • DOI: https://doi.org/10.3103/S1541308X11010122

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