Clinical Pharmacokinetics

, Volume 48, Issue 8, pp 489–516

Pharmacokinetic Optimization of Immunosuppressive Therapy in Thoracic Transplantation: Part II

Review Article

DOI: 10.2165/11317240-000000000-00000

Cite this article as:
Monchaud, C. & Marquet, P. Clin Pharmacokinet (2009) 48: 489. doi:10.2165/11317240-000000000-00000

Abstract

Part I of this article, which appeared in the previous issue of the Journal, reviewed calcineurin inhibitors —ciclosporin and tacrolimus. In part II, we review the pharmacokinetics and therapeutic drug monitoring of mycophenolate and mammalian target of rapamycin inhibitors — sirolimus and everolimus — in thoracic transplantation, and we provide an overall discussion and suggest various areas for future study.

Supplementary material

40262_2012_48080489_MOESM1_ESM.pdf (237 kb)
Supplementary material, approximately 242 KB.

Copyright information

© Adis Data Information BV 2009

Authors and Affiliations

  1. 1.INSERM Unit 850, CHU LimogesUniversity of LimogesLimogesFrance
  2. 2.INSERM U850, Department of Pharmacology and Toxicology — PharmacovigilanceHôpital Dupuytren, CHULimoges CEDEXFrance