American Journal of Clinical Dermatology

, Volume 11, Issue 1, pp 59–62

Coexistence of Basal Cell Carcinomas and Multiple Sebaceous Gland Hyperplasias in a Cyclosporine (Ciclosporin)-Treated Renal Transplant Recipient

Authors

    • Department of Dermatology, Faculty of MedicineKaradeniz Technical University
  • Hikmet Akyazi
    • Department of DermatologyFatih State Hospital
  • Sevgi Bahadir
    • Department of Dermatology, Faculty of MedicineKaradeniz Technical University
  • Köksal Alpay
    • Department of Dermatology, Faculty of MedicineKaradeniz Technical University
  • Ümit Çobanoğlu
    • Department of Pathology, Faculty of MedicineKaradeniz Technical University
Case Reports Cyclosporine-Induced BCC and Sebaceous Hyperplasia

DOI: 10.2165/11311120-000000000-00000

Cite this article as:
Yayli, S., Akyazi, H., Bahadir, S. et al. AM J Clin Dermatol (2010) 11: 59. doi:10.2165/11311120-000000000-00000

Abstract

A 55-year-old man presented with multiple, asymptomatic, yellowish papules on his face with a 4-year history, and two non-healing tumoral lesions on his nose with a 7-month history. He was a renal transplant recipient and had been treated with cyclosporine (ciclosporin) for 9 years. A biopsy from the asymptomatic, yellowish papule on the face showed sebaceous gland hyperplasia, and biopsies from the lesions on the nose revealed basal cell carcinomas. The lesions on the nose were excised.

Sebaceous gland hyperplasia and skin cancers are among the cutaneous neoplasms observed in renal transplant recipients receiving cyclosporine. To our knowledge, this is the third reported case of the coexistence of basal cell carcinomas and multiple sebaceous gland hyperplasias in a cyclosporine-treated renal transplant recipient.

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