Original Research Article


, Volume 27, Issue 7, pp 571-584

First online:

Costs of Illness in a Russian Cohort of Patients with Parkinson’s Disease

  • Yaroslav WinterAffiliated withDepartment of Neurology, Philipps University MarburgCenter for Mental Health, Klinikum Stuttgart, Eberhard-Karls-University
  • , Sonja von CampenhausenAffiliated withDepartment of Neurology, Philipps University MarburgDepartment of Neurology, Ludwig-Maximilians-University
  • , Georgy PopovAffiliated withDepartment of Neurology, Russian Medical State University
  • , Jens P. ReeseAffiliated withDepartment of Neurology, Philipps University Marburg
  • , Jens KlotscheAffiliated withDepartment of Psychology and Psychotherapy, Technical University
  • , Kai BötzelAffiliated withDepartment of Neurology, Ludwig-Maximilians-University
  • , Eugene GusevAffiliated withDepartment of Neurology, Russian Medical State University
  • , Wolfgang H. OertelAffiliated withDepartment of Neurology, Philipps University Marburg
  • , Richard DodelAffiliated withDepartment of Neurology, Philipps University Marburg Email author 
    • , Alla GuekhtAffiliated withDepartment of Neurology, Russian Medical State University

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Background: The economic burden associated with Parkinson’s disease (PD) is increasing as the worldwide population ages. While cost-of-illness studies for PD from developed countries have recently been published, data for Eastern Europe and Asia are still lacking.

Objective: To prospectively evaluate direct and indirect costs in a cohort of Russian patients with PD in order to identify cost-driving factors.

Methods and Patients: We recruited 100 patients with idiopathic PD who visited the outpatient department for movement disorders of the Russian Medical State University in Moscow between October 2004 and December 2005. The Unified Parkinson’s Disease Rating Scale was used to evaluate clinical status. Economic data were collected in a ‘bottom-up’ approach and evaluated from the societal perspective. Indirect costs were estimated using a human capital approach. Russian currency was converted into €, year 2005 values, using the purchasing power parity. All costs were then inflated to €, year 2008 values, using the Medical Care Component of the Consumer Price Index. Independent cost predictors were identified by means of multivariate regression analyses.

Results: From the societal perspective, total costs per patient over 6 months amounted to h2620 (95%CI 2050, 3200), with direct costs accounting for 67% and indirect costs for 33% of the total. Patients’ expenditures accounted for 43% of their private income. The primary burden on patients was due to informal care and drugs. Only 10% of home care was provided by the formal service sector. Costs for the nation are estimated at €1.1 billion per year.

Conclusion: The economic burden of PD in Russia is considerable, especially when taking into account low private incomes. Further development of a formal care system and better reimbursement systems for drugs are necessary in Russia.