American Journal of Clinical Dermatology

, Volume 8, Issue 4, pp 239–241

Merkel Cell Carcinoma in a Liver Transplant Patient

  • Houdna Ensaleh
  • Pascal Perney
  • Olivier Dereure
  • Jean-Jacques Guilhou
  • Bernard Guillot
Case Reports

DOI: 10.2165/00128071-200708040-00006

Cite this article as:
Ensaleh, H., Perney, P., Dereure, O. et al. Am J Clin Dermatol (2007) 8: 239. doi:10.2165/00128071-200708040-00006

Abstract

Merkel cell carcinoma (MCC) is an aggressive tumor, the incidence of which is seemingly increased in immunocompromised patients. We report on a new case of MCC occurring in a 69-year-old male liver transplant recipient 6.5 years after transplantation. The outcome was marked by early skin and lymph node relapses treated by radiotherapy alone, and the patient ultimately died 30 months after first diagnosis. Together with data from the literature, this case emphasizes the importance of early diagnosis and adequate management of this aggressive disease for which wide initial surgical excision, accurate staging, and close follow-up are of critical importance to outcome, especially in this setting of immunosuppressive treatment, which is usually associated with a higher rate of recurrence.

Copyright information

© Adis Data Information BV 2007

Authors and Affiliations

  • Houdna Ensaleh
    • 1
  • Pascal Perney
    • 2
  • Olivier Dereure
    • 1
  • Jean-Jacques Guilhou
    • 1
  • Bernard Guillot
    • 1
  1. 1.Department of DermatologyUniversity of Montpellier I, Hôpital Saint EloiMontpellier Cedex 5France
  2. 2.Department of Internal MedicineUniversity of Montpellier I, Hôpital Saint EloiMontpellierFrance

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