, Volume 22, Issue 12, pp 15-18

Choosing the form of nicotine replacement therapy (NRT) based on the individual smoker’s needs and preferences may improve abstinence rates

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Nasal polyposis is an extreme inflammatory condition of the upper airway. Polyps protruding into the nasal cavity cause persistent nasal blockage and reduced or abolished olfaction. Although often mild, the disease tends to have a long-term course requiring continuous treatment. Intranasal corticosteroids are effective in reducing the size and number of polyps and in alleviating nasal blockage. In cases of severe disease, short courses of systemic corticosteroids may be used together with intranasal formulations. Surgical options are mainly recommended when medication has proven inadequate.

Nicotine is the culprit

Nicotine is a highly addictive substance with a fundamental role in the initiation and maintenance of tobacco dependence.[1] When tobacco smoke is inhaled, nicotine is rapidly absorbed from the lungs and reaches the brain within 10–20 seconds, where it activates the mesolimbic dopaminergic reward pathway.[1] The peak in nicotine levels is followed by a gradual fall and, if nico