PharmacoEconomics

, Volume 22, Issue 3, pp 185–195

Cost Effectiveness of Interventions for Lateral Epicondylitis

Results from a Randomised Controlled Trial in Primary Care
  • Ingeborg B. C. Korthals-de Bos
  • Nynke Smidt
  • Maurits W. van Tulder
  • Maureen P. M. H. Rutten-van Mölken
  • Herman J. Adèr
  • Daniëlle A. W. M. van der Windt
  • Willem J. J. Assendelft
  • Lex M. Bouter
Original Research Article

DOI: 10.2165/00019053-200422030-00004

Cite this article as:
Korthals-de Bos, I.B.C., Smidt, N., van Tulder, M.W. et al. PharmacoEconomics (2004) 22: 185. doi:10.2165/00019053-200422030-00004

Abstract

Objective: Lateral epicondylitis is a common complaint, with an annual incidence between 1% and 3% in the general population. The Dutch College of General Practitioners in The Netherlands has issued guidelines that recommend a wait-and-see policy. However, these guidelines are not evidence based.

Design and setting: This paper presents the results of an economic evaluation in conjunction with a randomised controlled trial to evaluate the effects of three interventions in primary care for patients with lateral epicondylitis.

Patients and interventions: Patients with pain at the lateral side of the elbow were randomised to one of three interventions: a wait-and-see policy, corticosteroid injections or physiotherapy.

Main outcome measures and results: Clinical outcomes included general improvement, pain during the day, elbow disability and QOL. The economic evaluation was conducted from a societal perspective. Direct and indirect costs (in 1999 values) were measured by means of cost diaries over a period of 12 months. Differences in mean costs between groups were evaluated by applying non-parametric bootstrap techniques. The mean total costs per patient for corticosteroid injections were €430, compared with €631 for the wait-and-see policy and €921 for physiotherapy. After 12 months, the success rate in the physiotherapy group (91%) was significantly higher than in the injection group (69%), but only slightly higher than in the wait-and-see group (83%). The differences in costs and effects showed no dominance for any of the three groups. The incremental costutility ratios were (approximately): €7000 per utility gain for the wait-and-see policy versus corticosteroid injections; €12 000 per utility gain for physiotherapy versus corticosteroid injections, and €34 500 for physiotherapy versus the waitand- see policy.

Conclusions: The results of this economic evaluation provided no reason to update or amend the Dutch guidelines for GPs, which recommend a wait-and-see policy for patients with lateral epicondylitis.

Copyright information

© Adis Data Information BV 2004

Authors and Affiliations

  • Ingeborg B. C. Korthals-de Bos
    • 1
  • Nynke Smidt
    • 1
  • Maurits W. van Tulder
    • 1
    • 2
  • Maureen P. M. H. Rutten-van Mölken
    • 3
  • Herman J. Adèr
    • 2
  • Daniëlle A. W. M. van der Windt
    • 1
    • 4
  • Willem J. J. Assendelft
    • 5
  • Lex M. Bouter
    • 1
  1. 1.Institute for Research in Extramural MedicineVU University Medical CenterAmsterdamThe Netherlands
  2. 2.Department of Clinical Epidemiology and BiostatisticsVU University Medical CenterAmsterdamThe Netherlands
  3. 3.Institute for Medical Technology AssessmentErasmus UniversityRotterdamThe Netherlands
  4. 4.Department of General PracticeVU University Medical CenterAmsterdamThe Netherlands
  5. 5.Department of General Practice, Division of Public Health Academic Medical CenterUniversity of AmsterdamAmsterdamThe Netherlands