Review Article

Sports Medicine

, Volume 37, Issue 10, pp 895-906

First online:

Nutritional Interventions to Promote Post-Exercise Muscle Protein Synthesis

  • René KoopmanAffiliated withDepartment of Movement Sciences, Maastricht University Email author 
  • , Wim H.M. SarisAffiliated withDepartment of Human Biology, Nutrition and Toxicology Research Institute Maastricht (NUTRIM), Maastricht University
  • , Anton J.M. WagenmakersAffiliated withSchool of Sport and Exercise Sciences, University of Birmingham
  • , Luc J.C. van LoonAffiliated withDepartment of Movement Sciences, Maastricht University

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Resistance exercise is a powerful stimulus to augment muscle protein anabolism, as it can improve the balance between muscle protein synthesis and breakdown. However, the intake of food during post-exercise recovery is necessary for hypertrophy to occur. Therefore, athletes need to ingest protein following exercise to attain a positive protein balance and maximise their skeletal muscle adaptive response. The interaction between exercise and nutrition is not only important for athletes, but is also of important clinical relevance in the elderly. Exercise interventions combined with specific nutritional modulation provide an effective strategy to counteract or reduce the loss of skeletal muscle mass with aging.