, Volume 58, Issue 5, pp 793–797

Balanced Analgesia

What is it and What are its Advantages in Postoperative Pain?
  • Henrik Kehlet
  • Mads Werner
  • Frederick Perkins
Leading Article

DOI: 10.2165/00003495-199958050-00002

Cite this article as:
Kehlet, H., Werner, M. & Perkins, F. Drugs (1999) 58: 793. doi:10.2165/00003495-199958050-00002


The concept of balanced analgesia was introduced to improve analgesic efficacy and reduce adverse effects. A large amount of clinical data has documented improved analgesia by combining different analgesics, but data on reducing adverse effects are inconclusive. Balanced analgesia should be used whenever possible, and future studies should be directed to define optimal combination regimens in individual surgical procedures.

Copyright information

© Adis International Limited 1999

Authors and Affiliations

  • Henrik Kehlet
    • 1
  • Mads Werner
    • 2
  • Frederick Perkins
    • 3
  1. 1.Department of Surgical GastroenterologyHvidovre University HospitalHvidovreDenmark
  2. 2.Department of AnaesthesiologyHvidovre University HospitalHvidovreDenmark
  3. 3.Department of AnaesthesiologyRochester UniversityRochesterUSA