Leading Article


, Volume 58, Issue 5, pp 793-797

First online:

Balanced Analgesia

What is it and What are its Advantages in Postoperative Pain?
  • Henrik KehletAffiliated withDepartment of Surgical Gastroenterology, Hvidovre University Hospital
  • , Mads WernerAffiliated withDepartment of Anaesthesiology, Hvidovre University Hospital
  • , Frederick PerkinsAffiliated withDepartment of Anaesthesiology, Rochester University

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The concept of balanced analgesia was introduced to improve analgesic efficacy and reduce adverse effects. A large amount of clinical data has documented improved analgesia by combining different analgesics, but data on reducing adverse effects are inconclusive. Balanced analgesia should be used whenever possible, and future studies should be directed to define optimal combination regimens in individual surgical procedures.