Journal of Zhejiang University SCIENCE B

, Volume 7, Issue 10, pp 806–816

Computational prediction of microRNA genes in silkworm genome

Authors

  • Tong Chuan-zhou 
    • Institute of Biochemistry, School of Life ScienceZhejiang University
    • Institute of Biochemistry, School of Life ScienceZhejiang University
  • Zhang Yao-zhou 
    • Institute of Biochemistry, School of Life SciencesZhejiang Science and Technology University
Article

DOI: 10.1631/jzus.2006.B0806

Cite this article as:
Tong, C., Jin, Y. & Zhang, Y. J. Zhejiang Univ. - Sci. B (2006) 7: 806. doi:10.1631/jzus.2006.B0806

Abstract

MicroRNAs (miRNAs) constitute a novel, extensive class of small RNAs (∼21 nucleotides), and play important gene-regulation roles during growth and development in various organisms. Here we conducted a homology search to identify homologs of previously validated miRNAs from silkworm genome. We identified 24 potential miRNA genes, and gave each of them a name according to the common criteria. Interestingly, we found that a great number of newly identified miRNAs were conserved in silkworm and Drosophila, and family alignment revealed that miRNA families might possess single nucleotide polymorphisms. miRNA gene clusters and possible functions of complement miRNA pairs are discussed.

Key words

miRNASilkwormComputational prediction

CLC number

Q522

Copyright information

© Zhejiang University 2006