Journal of Zhejiang University SCIENCE B

, Volume 7, Issue 1, pp 56–63

Effects of two medicinal plants Psidium guajava L. (Myrtaceae) and Diospyros mespiliformis L. (Ebenaceae) leaf extracts on rat skeletal muscle cells in primary culture

  • Belemtougri R.G. 
  • Constantin B. 
  • Cognard C. 
  • Raymond G. 
  • Sawadogo L. 
Article

DOI: 10.1631/jzus.2006.B0056

Cite this article as:
Belemtougri, R., Constantin, B., Cognard, C. et al. J. Zhejiang Univ. - Sci. B (2006) 7: 56. doi:10.1631/jzus.2006.B0056

Abstract

Crude decoction, aqueous and ethanolic extracts of two medicinal plants (Psidium guajava and Diospyros mespiliformis), widely used in the central plateau of Burkina Faso to treat many diseases were evaluated for their antagonistic effects on caffeine induced calcium release from sarcoplasmic reticulum of rat skeletal muscle cells. These different extracts showed a decrease of caffeine induced calcium release in a dose dependent manner. Comparison of the results showed that Psidium guajava leaf extracts are more active than extracts of Diospyros mespiliformis and that crude decoctions show better inhibitory activity. The observed results could explaine their use as antihypertensive and antidiarrhoeal agents in traditional medicine, by inhibiting intracellular calcium release.

Key words

Psidium guajava Diospyros mespiliformis Myrtaceae Ebenaceae Medicinal plants Intracellular calcium Sarcoplasmic reticulum Caffeine 

Document code

CLC number

Q958.12+2.5 

Copyright information

© Zhejiang University 2006

Authors and Affiliations

  • Belemtougri R.G. 
    • 1
  • Constantin B. 
    • 2
  • Cognard C. 
    • 2
  • Raymond G. 
    • 2
  • Sawadogo L. 
    • 1
  1. 1.Laboratory of Physiological AnimalUniversity of OuagadougouBurkina FasoFrance
  2. 2.Institute of Physiology & Biology CellUniversity of PoitiersFrance

Personalised recommendations