Article

International Journal of Pancreatology

, Volume 29, Issue 1, pp 53-58

Adenosquamous carcinoma of the pancreas

Successful treatment with extended radical surgery, intraoperative radiation therapy, and locoregional chemotherapy
  • Hiroki YamaueAffiliated withSecond Department of Surgery, Wakayama Medical University, School of Medicine Email author 
  • , Hiroshi TanimuraAffiliated withSecond Department of Surgery, Wakayama Medical University, School of Medicine
  • , Hironobu OnishiAffiliated withSecond Department of Surgery, Wakayama Medical University, School of Medicine
  • , Masaji TaniAffiliated withSecond Department of Surgery, Wakayama Medical University, School of Medicine
  • , Hiroyuki KinoshitaAffiliated withSecond Department of Surgery, Wakayama Medical University, School of Medicine
  • , Manabu KawaiAffiliated withSecond Department of Surgery, Wakayama Medical University, School of Medicine
  • , Shozo YokoyamaAffiliated withSecond Department of Surgery, Wakayama Medical University, School of Medicine
  • , Kazuhisa UchiyamaAffiliated withSecond Department of Surgery, Wakayama Medical University, School of Medicine

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Summary

Background. Adenosquamous carcinoma of the pancreas is a rare tumor with an extremely poor survival rate. No obvious evidence that multidisciplinary treatments improves the prognosis and survival has been reported.

Patient and Results. A 63-yr-old female with adenosquamous carcinoma of the pancreas underwent extended radical surgery, intraoperative radiation therapy, postoperative intraarterial chemotherapy, and external beam radiation therapy. The patient is alive at 40 mo after surgery with no recurrence.

Conclusions. Multidisciplinary treatments including aggressive surgery, intraoperative radiation therapy, and locoregional chemotherapy might improve the survival of patients with adenosquamous carcinoma of the pancreas to inhibit liver metastasis and local recurrence.

Key Words

Adenosquamous carcinoma pancreatic cancer extended radical pancreaticoduodenectomy intraoperative radiation therapy intraarterial chemotherapy