Neuroinformatics

, Volume 1, Issue 4, pp 299–308

WebQTL

Web-based complex trait analysis
  • Jintao Wang
  • Robert W. Williams
  • Kenneth F. Manly
Original Article

DOI: 10.1385/NI:1:4:299

Cite this article as:
Wang, J., Williams, R.W. & Manly, K.F. Neuroinform (2003) 1: 299. doi:10.1385/NI:1:4:299

Abstract

WebQTL is a website that combines databases of complex traits with fast software for mapping quantitative trait loci (QTLs) and for searching for correlations among traits. WebQTL also includes well-curated genotype data for five sets of mouse recombinant inbred (RI) lines. Thus, to identify QTLs, users need provide only quantitative trait data from one of the supported populations. The WebQTL databases include both biological traits—neuroanatomical, pharmacological, and behavioral traits—and microarray-based gene expression data from BXD RI lines. A search function finds correlations between RNA expression and biological traits, and mapping functions find QTLs for either type of trait. The WebQTL service is available at http://www.webqtl.org/.

Index Entries

Geneticsgenetic mapquantitative traitcomplex traitmicroarraytranscriptomesoftwareweb service

Copyright information

© Humana Press Inc 2003

Authors and Affiliations

  • Jintao Wang
    • 1
  • Robert W. Williams
    • 2
  • Kenneth F. Manly
    • 1
  1. 1.Department of Molecular & Cellular BiologyRoswell Park Cancer InstituteBuffalo
  2. 2.Department of Anatomy and Neurobiology, Center of Genomics and BioinformaticsUniversity of Tennessee Health Science CenterMemphis