Original Article


, Volume 1, Issue 4, pp 299-308

First online:


Web-based complex trait analysis
  • Jintao WangAffiliated withDepartment of Molecular & Cellular Biology, Roswell Park Cancer Institute
  • , Robert W. WilliamsAffiliated withDepartment of Anatomy and Neurobiology, Center of Genomics and Bioinformatics, University of Tennessee Health Science Center
  • , Kenneth F. ManlyAffiliated withDepartment of Molecular & Cellular Biology, Roswell Park Cancer Institute Email author 

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WebQTL is a website that combines databases of complex traits with fast software for mapping quantitative trait loci (QTLs) and for searching for correlations among traits. WebQTL also includes well-curated genotype data for five sets of mouse recombinant inbred (RI) lines. Thus, to identify QTLs, users need provide only quantitative trait data from one of the supported populations. The WebQTL databases include both biological traits—neuroanatomical, pharmacological, and behavioral traits—and microarray-based gene expression data from BXD RI lines. A search function finds correlations between RNA expression and biological traits, and mapping functions find QTLs for either type of trait. The WebQTL service is available at http://www.webqtl.org/.

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Genetics genetic map quantitative trait complex trait microarray transcriptome software web service