Molecular Biotechnology

, Volume 35, Issue 1, pp 65–97

Online resources for SNP analysis

A review and route map
Review

DOI: 10.1385/MB:35:1:65

Cite this article as:
Phillips, C. Mol Biotechnol (2007) 35: 65. doi:10.1385/MB:35:1:65

Abstract

The major online single nucleotide polymorphism (SNP) databases freely available as research tools for genetic analysis are explained, reviewed, and compared. An outline is given of the search strategies that can be used with the most extensive current SNP databases: National Centre for Biotechnology Information (NCBI) dbSNP and HapMap to help the use secure the most appropriate data for the research needs of clinical genetics and population genetics research. A range of online tools that can be useful in designing SNP genotyping assays are also detailed.

Index Entries

Single nucleotide polymorphismSNPgenotypingvariationpolymorphismonline data-baseslinkage disequilibriumhaplotypehaplotype blockgenomeHapMapclinical geneticspopulation gegetics

Copyright information

© Humana Press Inc 2006

Authors and Affiliations

  1. 1.The Spanish National Genotyping Centre CeGen, Santiago node Genomic Medicine GroupUniversity of Santiago de CompostelaGaliciaSpain