Immunologic Research

, Volume 21, Issue 2, pp 63-69

First online:

A role for epithelial γδ T cells in tissue repair

  • Wendy L. HavranAffiliated withDepartment of Immunology, IMMS, The Scripps Research Institute

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My colleagues and I have a long-term interest in interactions between intraepithelial γδ T cells and neighboring epithelial cells. We have focused our studies on interactions in the thymus, skin, and intestine, and are investigating the development, specificity, and function of these γδ T cells. Our results have defined unique properties of these cells and support a specialized role for epithelial γδ T cells in immune surveillance, wound repair, inflammation, and protection from malignancy.

Key words

γδ T cells Wound healing Cytokines KGF