Abstract
Calcitonin has been shown to be a progesterone-regulated potential marker of the receptive endometrium in the rat and human. The present study was undertaken to immunohistochemically investigate the changes in calcitonin in the monkey uterus during the menstrual cycle and periimplantation period. Calcitonin immunostaining was primarily localized in the glandular epithelium on d 16, 20, and 25 of the menstrual cycle. During early pregnancy, calcitonin immunostaining was strongly observed in the glandular epithelium only on d 9 of pregnancy, the day before implantation. Since the high level of calcitonin immunostaining in the glandular epithelium during the luteal phase of the menstrual cycle and periimplantation period matched the high level of maternal progesterone during this period, the expression of calcitonin in monkey endometrium may be under the regulation of maternal progesterone.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Austin, L. A. and Heath, H., (1981). N. Engl. J. Med. 304, 269–278.
Becker, K. L., Snider, R., Moore, C. F., Monaghan, K. G., and Silva, O. L. (1979). Acta Endocrinol. 92, 746–751.
Fischer, J. A., Tobler, P. H., Kaufmann, M., Born, W., Henke, H., Cooper, P. E., Sagar, S. M.; and Martin, J. B. (1981). Proc. Natl. Acad. Sci. USA 78, 7801–7805.
Ding, Y. Q., Zhu, L. J., Bagchi, M. K., and Bagchi, I. C. (1994). Endocrinology 135, 2265–2274.
Zhu, L. J., Cullinan-Bove, K., Polihronis, M., Bagchi, M. K., and Bagchi, I. C. (1998a). Endocrinology 139, 3923–3934.
Zhu, L. J., Bagchi, M. K., and Bagchi, I. C. (1998b). Endocrinology 139, 330–339.
Kumar, S., Zhu, L. J., Polihronis, M., Cameron, S. T., Baird, D. T., Schatz, F., Dua, A., Ying, Y. K., Bagchi, M. K., and Bagchi, I. C. (1998). J. Clin. Endocrinol. Metab. 83, 4443–4450.
Enders, A. C., Hendrickx, A. G., and Schlafke, S. (1983). Am. J. Anat. 167, 275–298.
Hearn, J. P., Webley, G. E., and Gidley-Baird, A. A. (1991). J. Reprod. Fertil. 92, 497–509.
Stewart, C. L., Kaspar, P., Brunet, L. J., Bhatt, H., Gadi, I., Kontgen, F., and Abbondanzo, S. J. (1992). Nature 359, 76–79.
Yue, Z. P., Yang, Z. M., Wei, P., Li, S. J., Wang, H. B., Tan, J. H., and Harper, M. J. K. (2000). Biol. Reprod. 63, 508–512.
Baulieu, E. E. (1991). Trends Endocrinol. Metab. 2, 233–239.
Ghosh, D., De, P., and Sengupta, J. (1994). Hum. Reprod. 9, 629–637.
Zegers-Hoshchild, F. and Altieri, E. (1995). J. Assist. Reprod. Genet. 12, 224–228.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Diao, HL., Li, SJ., Wang, HB. et al. Calcitonin immunostaining in monkey uterus during menstrual cycle and early pregnancy. Endocr 18, 75–78 (2002). https://doi.org/10.1385/ENDO:18:1:75
Received:
Revised:
Accepted:
Issue Date:
DOI: https://doi.org/10.1385/ENDO:18:1:75