Chromatographia

, Volume 67, Issue 5, pp 425–431

Determination of Antioxidants and Preservatives in Cosmetics by SPME Combined with GC–MS

Original

DOI: 10.1365/s10337-007-0514-1

Cite this article as:
Tsai, T. & Lee, M. Chroma (2008) 67: 425. doi:10.1365/s10337-007-0514-1
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Abstract

A rapid and simple procedure for the determination of antioxidants and preservatives in cosmetics has been developed utilizing solid-phase microextraction combined with GC–MS. A silica fiber coated with polyacrylate provided the highest extraction efficiency. Detection limits in the range from 0.4 to 8.5 ng mL−1 were obtained. Linearity is over a wide range from 1 to 2,000 ng mL−1 with a relative standard deviation under 16%. Cosmetic from a local supermarket were analysed for antioxidants and preservatives to demonstrate the effectiveness of the proposed method. The concentration of antioxidants and preservatives determined was 20–1,218 μg g−1 for methylparaben and 5–3,779 μg g−1 for propylparaben.

Keywords

GC–MSSolid-phase microextractionPreservatives and antioxidantsCosmetics

Copyright information

© Friedr. Vieweg & Sohn Verlag/GWV Fachverlage GmbH 2008

Authors and Affiliations

  1. 1.Department of ChemistryNational Chung Hsing UniversityTaichungTaiwan
  2. 2.Department of Cosmetic ScienceProvidence UniversityTaichungTaiwan