Simultaneous Determination of Cefuroxime Axetil and Cefuroxime in Pharmaceutical Preparations by Thin-Layer Chromatography and Densitometry
Purchase on Springer.com
$39.95 / €34.95 / £29.95*
Rent the article at a discountRent now
* Final gross prices may vary according to local VAT.
Conditions have been established for identification and quantification of cefuroxime axetil and cefuroxime by thin-layer chromatography and densitometry. Good separation of these compounds was achieved on silica gel by use of chloroform–ethyl acetate–glacial acetic acid–water, 4:4:4:1 (v/v), as mobile phase. UV densitometry was used to detect spots on chromatograms. Under these conditions the limits of detection for cefuroxime axetil and cefuroxime were 40 ng and 30 ng, respectively. Recoveries of cefuroxime axetil and cefuroxime were 99.93% and 97.94%, respectively.
- Simultaneous Determination of Cefuroxime Axetil and Cefuroxime in Pharmaceutical Preparations by Thin-Layer Chromatography and Densitometry
Volume 58, Issue 3-4 , pp 231-234
- Cover Date
- Print ISSN
- Online ISSN
- Vieweg Verlag
- Additional Links
- Thin-layer chromatography Densitometric detection Cefuroxime axetil and cefuroxime
- Industry Sectors