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Outcomes of Concurrent Breast and Gynecologic Risk Reduction Surgery

  • Breast Oncology
  • Published:
Annals of Surgical Oncology Aims and scope Submit manuscript

Abstract

Background

Women considering risk reduction surgery after a diagnosis of breast/ovarian cancer and/or inherited cancer gene mutation face difficult decisions. The safety of combined breast and gynecologic surgery has not been well studied; therefore, we evaluated the outcomes for patients who have undergone coordinated multispecialty surgery.

Methods

We conducted a retrospective review of patients undergoing simultaneous breast and gynecologic surgery for newly or previously diagnosed breast cancer and/or an inherited cancer gene mutation during the same anesthetic at a single institution from 1999 to 2013.

Results

Seventy-three patients with a mean age of 50 years (range 27–88) were identified. Most patients had newly diagnosed breast cancer or ductal carcinoma in situ (62 %) and 28 patients (38 %) had an identified BRCA mutation. Almost all gynecologic procedures were for risk reduction or benign gynecologic conditions (97 %). Mastectomy was performed in 39 patients (53 %), the majority of whom (79 %) underwent immediate reconstruction. The most common gynecologic procedure involved bilateral salpingo-oophorectomy, which was performed alone in 18 patients (25 %) and combined with hysterectomy in 40 patients (55 %). A total of 32 patients (44 %) developed postoperative complications, most of which were minor and did not require surgical intervention or hospitalization. Two of the 19 patients who underwent implant reconstruction (11 %; 3 % of the entire cohort) had major infectious complications requiring explantation.

Conclusion

Combined breast and gynecologic procedures for a breast cancer diagnosis and/or risk reduction in patients can be accomplished with acceptable morbidity. Concurrent operations, including reconstruction, can be offered to patients without negatively impacting their outcome.

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Authors and Affiliations

  1. Department of Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA

    Irene T. Ma MD, Richard J. Gray MD, Nabil Wasif MD, MPH & Barbara A. Pockaj MD

  2. Department of Gynecology, Mayo Clinic Arizona, Phoenix, AZ, USA

    Kristina A. Butler MD, Jeffrey L. Cornella MD, Javier F. Magrina MD & Paul M. Magtibay MD

  3. Division of Plastic Surgery, Mayo Clinic Arizona, Phoenix, AZ, USA

    William J. Casey MD, Raman Mahabir MD & Alanna M. Rebecca MD, MPH

  4. Division of Hematology/Oncology, Mayo Clinic Arizona, Phoenix, AZ, USA

    Katherine S. Hunt MS, PhD, CGC

Authors
  1. Irene T. Ma MD
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  2. Richard J. Gray MD
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  3. Nabil Wasif MD, MPH
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  4. Kristina A. Butler MD
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  5. Jeffrey L. Cornella MD
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  6. Javier F. Magrina MD
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  7. Paul M. Magtibay MD
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  8. William J. Casey MD
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  9. Raman Mahabir MD
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  10. Alanna M. Rebecca MD, MPH
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  11. Katherine S. Hunt MS, PhD, CGC
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  12. Barbara A. Pockaj MD
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Corresponding author

Correspondence to Barbara A. Pockaj MD.

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Ma, I.T., Gray, R.J., Wasif, N. et al. Outcomes of Concurrent Breast and Gynecologic Risk Reduction Surgery. Ann Surg Oncol 24, 77–83 (2017). https://doi.org/10.1245/s10434-016-5479-6

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  • DOI: https://doi.org/10.1245/s10434-016-5479-6

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