References
Deisboeck TS. Personalizing medicine: a systems biology perspective. Mol Syst Biol. 2009;5:249. Epub 2009 Mar 17.
Roukos DH. Mea culpa with cancer-targeted therapy: new thinking and new agents design for novel, causal networks-based, personalized biomedicine. Expert Rev Mol Diagn. 2009;9(3):217–21.
Garber AM, Tunis SR. Does comparative-effectiveness research threaten personalized medicine? N Engl J Med. 2009;360(19):1925–7.
Jones S, Zhang X, Parsons DW. Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science. 2008;321(5897):1801–6.
Fukagawa T, Sasako M, Shimoda T, et al. The prognostic impact of isolated tumor cells in lymph nodes of T2N0 gastric cancer: comparison of American and Japanese gastric cancer patients. Ann Surg Oncol. 2009;16(3):609–13.
Roukos DH. Breast cancer outcomes: the crucial role of the breast surgeon in the era of personal genetics and systems biology. Ann Surg. 2009;249(6):1067–8.
Roukos DH. Personalized cancer diagnostics and therapeutics. Expert Rev Mol Diagn. 2009;9(3):227–9.
Roukos DH. Radiation therapy for breast cancer. N Engl J Med. 2009;360(13):1362; author reply 1363.
Roukos DH. Twenty-one-gene assay: challenges and promises in translating personal genomics and whole-genome scans into personalized treatment of breast cancer. J Clin Oncol. 2009;27(8):1337–8; author reply 1338–9.
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Ziogas, D.E., Roukos, D.H. Limitations of Isolated Tumor Cells in Gastric Cancer: Heterogeneity Requests Systems Biology Approaches Towards Personalized Medicine. Ann Surg Oncol 17, 343–344 (2010). https://doi.org/10.1245/s10434-009-0747-3
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DOI: https://doi.org/10.1245/s10434-009-0747-3