Annals of Surgical Oncology

, Volume 21, Issue 7, pp 2353–2360

Comparison of Two Preoperative Inspiratory Muscle Training Programs to Prevent Pulmonary Complications in Patients Undergoing Esophagectomy: A Randomized Controlled Pilot Study

  • Edwin J. van Adrichem
  • Renée L. Meulenbroek
  • John T. M. Plukker
  • Henk Groen
  • Ellen van Weert
Thoracic Oncology

DOI: 10.1245/s10434-014-3612-y

Cite this article as:
van Adrichem, E.J., Meulenbroek, R.L., Plukker, J.T.M. et al. Ann Surg Oncol (2014) 21: 2353. doi:10.1245/s10434-014-3612-y

Abstract

Background

Postoperative pulmonary complications (PPCs) are the most commonly reported complications after esophagectomy. The aim of this study was to examine the effect and feasibility of preoperative inspiratory muscle training-high intensity (IMT-HI), and IMT-endurance (IMT-E) on the incidence of PPCs in patients following esophagectomy for esophageal cancer (EC).

Method

A single-blind, randomized, clinical pilot study was conducted between 2009 and 2012. Forty-five participants were assigned to either IMT-HI or IMT-E. Effectiveness was assessed by analyzing PPCs, length of hospital stay (LOS), duration of mechanical ventilation, stay on the intensive care unit, and number of reintubations. Maximal inspiratory pressure and lung function changes were recorded pre- and post-training. Feasibility was assessed by IMT-related adverse events, training compliance, and patients’ satisfaction.

Results

Thirty-nine patients could be analyzed, 20 patients in the IMT-HI arm and 19 patients in the IMT-E arm. The incidence of PPCs differed significantly between groups and was almost three times lower for the IMT-HI group (4 vs. 11 patients; p = 0.015). Other differences in favor of the IMT-HI group were LOS (13.5 vs. 18 days; p = 0.010) and number of reintubations (0 vs. 4 patients; p = 0.030). Both interventions proved to be equally feasible.

Conclusion

Preoperative IMT-HI showed to be a promising, effective, and feasible intervention to reduce PPCs in EC patients undergoing esophagectomy. Further research with a larger sample size is recommended.

Copyright information

© Society of Surgical Oncology 2014

Authors and Affiliations

  • Edwin J. van Adrichem
    • 1
  • Renée L. Meulenbroek
    • 1
  • John T. M. Plukker
    • 2
  • Henk Groen
    • 3
  • Ellen van Weert
    • 4
  1. 1.Department of Rehabilitation MedicineUniversity of Groningen, University Medical Centre Groningen (UMCG)GroningenThe Netherlands
  2. 2.Department of Surgical OncologyUniversity of Groningen, University Medical Centre Groningen (UMCG)GroningenThe Netherlands
  3. 3.Department of EpidemiologyUniversity of Groningen, University Medical Centre Groningen (UMCG)GroningenThe Netherlands
  4. 4.Centre for RehabilitationUniversity of Groningen, University Medical Centre Groningen (UMCG)GroningenThe Netherlands