Annals of Surgical Oncology

, Volume 13, Issue 4, pp 480–482

Significance of Papillary Lesions at Percutaneous Breast Biopsy

Authors

    • Department of SurgeryComprehensive Breast Service, St. Luke’s Roosevelt Medical Center
  • Paul I. Tartter
    • Department of SurgeryComprehensive Breast Service, St. Luke’s Roosevelt Medical Center
  • Elvita Genelus-Dominique
    • Department of SurgeryComprehensive Breast Service, St. Luke’s Roosevelt Medical Center
  • Deborah-Alexis Guilbaud
    • Department of RadiologyComprehensive Breast Service, St. Luke’s Roosevelt Medical Center
  • Sharon Rosenbaum-Smith
    • Department of SurgeryComprehensive Breast Service, St. Luke’s Roosevelt Medical Center
  • Alison Estabrook
    • Department of SurgeryComprehensive Breast Service, St. Luke’s Roosevelt Medical Center
Article

DOI: 10.1245/ASO.2006.08.001

Cite this article as:
Valdes, E.K., Tartter, P.I., Genelus-Dominique, E. et al. Ann Surg Oncol (2006) 13: 480. doi:10.1245/ASO.2006.08.001

Abstract

Background

The management of nonpalpable papillary lesions found in specimens obtained by percutaneous breast biopsy is controversial. We reviewed the treatment of patients found to have papillary lesions by stereotactic, sonographic, or fine-needle aspiration breast biopsy to identify indications for surgical excision.

Methods

Consecutive patients with intraductal papilloma, atypical papilloma/papilloma with atypical ductal hyperplasia, papillary neoplasm, and papillomatosis according to percutaneous breast biopsy were identified from radiology records. The charts were reviewed to identify patients who had subsequent surgical excision, and the pathologic findings were correlated with the biopsy method and indications for surgery.

Results

Papillary lesions were found in 120 biopsy samples from 109 patients. Malignancy was found at operation in 19 (24%) of 80 lesions that underwent surgical excision: 12 (63%) were ductal carcinoma-in-situ, 4 (21%) were infiltrating ductal carcinoma, 2 (11%) were infiltrating papillary carcinoma, and 1 (5%) was intracystic papillary carcinoma. Malignancy was found in 9 (30%) of 30 fine-needle biopsy papillary lesions, 6 (35%) of 17 core biopsy papillary lesions, and 4 (12%) of 33 stereotactic biopsy papillary lesions. Malignancy was missed significantly less frequently with stereotactic biopsy (P < .05).

Conclusions

Malignancy is frequently found at surgical excision for papillary lesions found on percutaneous breast biopsy. Malignancy is missed significantly less frequently with stereotactic biopsy.

Keywords

Papillary lesionPapillary neoplasmIntraductal papillomaPapillomatosisPapillary carcinomaPercutaneous breast biopsy

Copyright information

© The Society of Surgical Oncology, Inc. 2006