, Volume 13, Issue 3, pp 323-327

Hidalgo, I. J., Raub, T. J., and Borchardt, R. T.: Characterization of the Human Colon Carcinoma Cell Line (Caco-2) as a Model System for Intestinal Epithelial Permeability, Gastroenterology, 96, 736–749, 1989—The Backstory

This is an excerpt from the content

In 1983, I was offered the opportunity to become Chairman and Solon E. Summerfield Distinguished Professor in the Department of Pharmaceutical Chemistry in the School of Pharmacy at The University of Kansas (KU), Lawrence, KS. Prior to that time, I had been a faculty member in the Departments of Biochemistry and Medicinal Chemistry at KU for 12 years and my research interests were focused on the design and synthesis of enzyme inhibitors having potential medical applications in the treatment of viral and parasite infections and neurological diseases.

My decision to accept these new academic positions in KU’s Department of Pharmaceutical Chemistry was based in part on the opportunities that I saw to expand the scientific breadth of this department to include pharmaceutical biotechnology and cellular and molecular biopharmaceutics. Through the leadership provided by the late Professor Takeru Higuchi, who was the founder and the first Chairman of KU’s Department of Pharmaceutical Chemistry,

Editor: Ho-Leung Fung