Annals of Intensive Care

, 2:42

First online:

Open Access This content is freely available online to anyone, anywhere at any time.

Management of thrombocytopenia in the ICU (pregnancy excluded)

  • Thierry Van der LindenAffiliated withService de Réanimation Polyvalente, groupe hospitalier Institut Catholique de Lille/Faculté Libre de Médecine/Université Lille Nord de France Email author 
  • , Bertrand SouweineAffiliated withService de Réanimation Polyvalente, CHU Gabriel Montpied
  • , Laurent DupicAffiliated withService de Réanimation Médico-Chirurgicale, CHU Necker Enfants Malades
  • , Lilia SoufirAffiliated withService de Réanimation Chirurgicale, Groupe Hospitalier Paris Saint Joseph
  • , Pascal MeyerAffiliated withService de Réanimation Polyvalente, CH Sud Francilien Site de Corbeil


Thrombocytopenia is a very frequent disorder in the intensive care unit. Many etiologies should be searched, and therapeutic approaches differ according to these different causes. However, no guideline exists regarding optimum practices for these situations in critically ill patients. We present recommendations for the management of thrombocytopenia in intensive care unit, excluding pregnancy, developed by an expert group of the French-Language Society of Intensive Care (Société de Réanimation de Langue Française (SRLF), the French Language Group of Paediatric Intensive Care and Emergencies (GFRUP) and of the Haemostasis and Thrombosis Study Group (GEHT) of the French Society of Haematology (SFH). The recommendations cover six fields of application: definition, epidemiology, and prognosis; diagnostic approach; therapeutic aspects; thrombocytopenia and sepsis; iatrogenic thrombocytopenia, with a special focus on heparin-induced thrombocytopenia; and thrombotic microangiopathy.


Thrombocytopenia Critical care Adults Expert recommendations