Primary thyroid angiosarcoma: an unusual localization
The finding of thyroid nodules is a very common occurrence in routine clinical practice. Approximately 5% to 7% of the entire population have thyroid nodules. Vascular lesions are one of the most controversial issues in thyroid pathology. These include benign lesions such as hemangiomas and, rarely, malignant tumors such as angiosarcomas or undifferentiated angiosarcomatoid carcinomas. In particular, angiosarcoma of the thyroid gland is a rare, highly aggressive malignant vascular tumor and in Italy the greatest geographical incidence of this lesion is witnessed near the Alps. Here, a case of thyroid angiosarcoma in a 71-year-old man with a history of goiter for about 20 years is described. The unusual localization of this lesion, the difficulties in reaching a definitive diagnosis for this particular histological type of primary tumor and a history of long-standing multinodular goiter in thyroid of an older man from outside the Alpine region prompted us to report this case of thyroid angiosarcoma mainly to discuss surgical, histopathological and immunohistochemical features.
- Primary thyroid angiosarcoma: an unusual localization
- Open Access
- Available under Open Access This content is freely available online to anyone, anywhere at any time.
World Journal of Surgical Oncology
- Online Date
- May 2012
- Online ISSN
- BioMed Central
- Additional Links
- Non-alpine region
- Old man
- Author Affiliations
- 1. Department of Gerontology, Geriatry and Metabolic Diseases, UOC of General and Geriatric Surgery, School of Medicine, Second University of the Study of Naples, Piazza Miraglia, 80138, Naples, Italy
- 2. Department of Public, Clinic and Preventive Medicine, Division of Pathology, School of Medicine, Second University of the Study of Naples, L. Armanni, 80138, Naples, Italy