, Volume 31, Issue 5, pp 388-401
Date: 10 Jan 2014

Psychosomatic Medicine: The Scientific Foundation of the Biopsychosocial Model

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This article presents major concepts and research findings from the field of psychosomatic medicine that the authors believe should be taught to all medical students.


The authors asked senior scholars involved in psychosomatic medicine to summarize key findings in their respective fields.


The authors provide an overview of the field and summarize core research in basic psychophysiological mechanisms—central nervous system/autonomic nervous system, psychoneuroimmunology, and psychoendocrinology—in three major disease states—cardiovascular, gastrointestinal, and HIV virus infections.


Understanding the core scientific concepts and research findings of psychosomatic medicine should provide medical trainees with a scientific foundation for practicing medicine within a biopsychosocial model of care.