Limiting values of diffusion coefficients of glycine, alanine, \(\alpha\)-amino butyric acid, norvaline and norleucine in a relevant physiological aqueous medium

  • Diana M. Rodriguez
  • Luis M. P. Verissimo
  • Marisa C. F. Barros
  • Daniela F. S. L. Rodrigues
  • Maria Melia Rodrigo
  • Miguel A. Esteso
  • Carmen M. Romero
  • Ana C. F. Ribeiro
Regular Article

DOI: 10.1140/epje/i2017-11511-y

Cite this article as:
Rodriguez, D.M., Verissimo, L.M.P., Barros, M.C.F. et al. Eur. Phys. J. E (2017) 40: 21. doi:10.1140/epje/i2017-11511-y
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Part of the following topical collections:
  1. Non-isothermal transport in complex fluids

Abstract.

The side chain effect on transport in ionic aqueous salt solutions was investigated for \(\alpha\)-amino acids glycine, alanine, \(\alpha\)-amino butyric acid, norvaline, and norleucine --that together define a chemical homologous series based on the length of the characteristic side chain which increases from zero to four carbons, respectively. Binary mutual diffusion coefficients at infinitesimal concentration in aqueous solutions of NaCl (0.15 mol kg-1) are measured by means of Taylor dispersion technique for this series and significant differences were found against previous published results for identical systems in pure water. In this way, NaCl effect on the transport of each amino acid is thus assessed and discussed in terms of salting-out effects. Also, solvated Stokes hydrodynamic radii were computed for the series showing comparable results in water and NaCl solution. The new information should prove useful in the design and characterization of transport-controlled systems in physiological and pharmacological studies.

Graphical abstract

Keywords

Topical Issue: Non-isothermal transport in complex fluids 

Copyright information

© EDP Sciences, SIF, Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Diana M. Rodriguez
    • 1
  • Luis M. P. Verissimo
    • 2
    • 3
  • Marisa C. F. Barros
    • 2
    • 3
  • Daniela F. S. L. Rodrigues
    • 2
  • Maria Melia Rodrigo
    • 3
  • Miguel A. Esteso
    • 2
    • 3
  • Carmen M. Romero
    • 1
  • Ana C. F. Ribeiro
    • 2
  1. 1.Departamento de Química, Facultad de CienciasUniversidad Nacional de Colombia Sede BogotáBogotá D.C.Colombia
  2. 2.Department of ChemistryUniversity of CoimbraCoimbraPortugal
  3. 3.U.D. Química FísicaUniversidad de AlcaláMadridSpain