The European Physical Journal B

, 86:165

Hybrid Bio-Mag-MEMS combining magnetophoresis and dielectrophoresis

Authors

    • G2Elab, CNRS UMR 5269 and Grenoble University
    • LMGP, CNRS UMR 5628 and Grenoble-INP
  • Alain Masse
    • G2Elab, CNRS UMR 5269 and Grenoble University
  • Luiz Fernando Zanini
    • G2Elab, CNRS UMR 5269 and Grenoble University
    • Néel Institute, CNRS UPR 2940 and Joseph Fourier University
  • Victor Gaude
    • G2Elab, CNRS UMR 5269 and Grenoble University
  • Sarah Delshadi
    • G2Elab, CNRS UMR 5269 and Grenoble University
  • Thibault Honegger
    • LTM, CNRS UMR 5129 and CEA Grenoble
  • David Peyrade
    • LTM, CNRS UMR 5129 and CEA Grenoble
  • Marianne Weidenhaupt
    • LMGP, CNRS UMR 5628 and Grenoble-INP
  • Frédéric Dumas-Bouchiat
    • Néel Institute, CNRS UPR 2940 and Joseph Fourier University
  • Franz Bruckert
    • LMGP, CNRS UMR 5628 and Grenoble-INP
  • Orphée Cugat
    • G2Elab, CNRS UMR 5269 and Grenoble University
  • Gilbert Reyne
    • G2Elab, CNRS UMR 5269 and Grenoble University
Regular Article

DOI: 10.1140/epjb/e2013-30679-1

Cite this article as:
Blaire, G., Masse, A., Zanini, L.F. et al. Eur. Phys. J. B (2013) 86: 165. doi:10.1140/epjb/e2013-30679-1
Part of the following topical collections:
  1. Topical issue: New Trends in Magnetism and Magnetic Materials

Abstract

The design of a new hybrid magnetic MEMS for biology (Bio-Mag-MEMS) is presented. It combines magnetophoresis, dielectrophoresis and microfluidics. These phenomena are used to sort magnetically tagged and non-tagged objects. Magnetic objects are trapped by the use of high gradient magnetophoresis. Thanks to dielectrophoresis these objects, once trapped, can be successfully released in a buffer. Efficient sorting is performed in this hybrid Bio-Mag-MEMS by using magnetic beads. A high sorting efficiency is demonstrated. Magnetic, Stokes and dielectrophoretic forces in the microfluidic channel are simulated with both analytical tools and the finite element method (FEM). The trajectories of magnetically tagged objects are simulated. Finally the fabrication and optimization of this device are detailed.

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Copyright information

© EDP Sciences, SIF, Springer-Verlag Berlin Heidelberg 2013