The European Physical Journal B - Condensed Matter and Complex Systems

, Volume 46, Issue 1, pp 1–8

Position control and optical manipulation for nanotechnology applications

Solid and Condensed State Physics

DOI: 10.1140/epjb/e2005-00232-2

Cite this article as:
Capitanio, M., Cicchi, R. & Pavone, F. Eur. Phys. J. B (2005) 46: 1. doi:10.1140/epjb/e2005-00232-2


During the last decade, great advances have been made concerning the construction and manipulation of nanostructures. As a consequence, nanometer stability and control of the sample position have became crucial points. For this purpose, we have built an optical microscope with high mechanic stability and we have implemented a feedback system in order to compensate thermal drifts. We demonstrate the system stability to be within one nanometer, with a control on the sample position of some micrometers, along the three spatial directions. The sample can be manipulated optically by means of a multiple optical tweezers setup and its displacements measured with a 3D position detector. We discuss and characterize the system properties thoroughly. We finally test the apparatus on a bio-molecular system constituted by a single myosin motor interacting with an actin filament.

Copyright information

© EDP Sciences/Società Italiana di Fisica/Springer-Verlag 2005

Authors and Affiliations

  1. 1.Italy and Dipartimento di Biologia Animale e Genetica “Leo Pardi”LENS, Via Nello Carrara 1, 50019 Sesto Fiorentino, FirenzeFirenzeItaly
  2. 2.LENS, Via Nello Carrara 1, 50019 Sesto Fiorentino, Firenze, Italy and Dipartimento di Fisica-Università degli Studi di FirenzeFirenzeItaly