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New synthesis of 3,5-diaryl-1,2,4-oxadiazoles containing a sulfonyl chloride or sulfonamide group

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Abstract

A procedure has been developed for the indirect introduction of sulfonyl chloride and sulfonamide groups into 3,5-diaryl-1,2,4-oxadiazoles via acylation of N′-hydroxybenzimidamide with aromatic and heterocyclic sulfocarboxylic acid dichlorides. The acylation selectively involves the carbonyl chloride group, regardless of the dichloride structure.

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Correspondence to P. A. Agat’ev.

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Original Russian Text © P.A. Agat’ev, R.M. Shlenev, A.V. Tarasov, A.S. Danilova, 2015, published in Zhurnal Organicheskoi Khimii, 2015, Vol. 51, No. 7, pp. 1006–1009.

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Agat’ev, P.A., Shlenev, R.M., Tarasov, A.V. et al. New synthesis of 3,5-diaryl-1,2,4-oxadiazoles containing a sulfonyl chloride or sulfonamide group. Russ J Org Chem 51, 988–991 (2015). https://doi.org/10.1134/S1070428015070167

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  • DOI: https://doi.org/10.1134/S1070428015070167

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