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Synthesis and alkylation of new 3-functionally substituted carbo[c]fused pyridin-2-ones(thiones)

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Abstract

By condensation of 2-acyl-1-(morpholin-4-yl)cycloalkenes with CH-acids new 3-functuinally substituted carbo[c]fused pyridin-2-ones(thiones) were synthesized. N, 1-Diphenyl-5, 6, 7, 8-tetrahydroisoquinoline-3-thione under the action of acrylonitrile and alkyl halides suffered a selective S-alkylation.

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Authors and Affiliations

  1. Taras Shevchenko Lugansk National University, Lugansk, 91011, Ukraine

    I. V. Dyachenko

  2. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev, Ukraine

    M. V. Vovk

Authors
  1. I. V. Dyachenko
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  2. M. V. Vovk
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Correspondence to I. V. Dyachenko.

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Original English Text © I.V. Dyachenko, M.V. Vovk, 2013, published in Zhurnal Organicheskoi Khimii, 2013, Vol. 49, No. 2, pp. 268–275.

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Dyachenko, I.V., Vovk, M.V. Synthesis and alkylation of new 3-functionally substituted carbo[c]fused pyridin-2-ones(thiones). Russ J Org Chem 49, 259–267 (2013). https://doi.org/10.1134/S1070428013020139

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  • DOI: https://doi.org/10.1134/S1070428013020139

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