Russian Journal of Organic Chemistry

, Volume 42, Issue 3, pp 365–368

Synthesis of chiral 5-aryltetrahydrofuran-2-ones via yeast bioreduction of γ-keto acids and their esters

Authors

  • N. O. Mahmoodi
    • Organic Research LaboratoryDepartment of Chemistry University of Guilan
  • R. Yousefi-Malekroudi
    • Organic Research LaboratoryDepartment of Chemistry University of Guilan
Article

DOI: 10.1134/S1070428006030043

Cite this article as:
Mahmoodi, N.O. & Yousefi-Malekroudi, R. Russ J Org Chem (2006) 42: 365. doi:10.1134/S1070428006030043

Abstract

Enantioselective reduction of γ-keto acids and related γ-keto esters with Saccharomyces cerevisiae (baker’s yeast) leads to the formation of the corresponding chiral 5-aryltetrahydrofuran-2-ones in satisfactory chemical and optical yields.

Copyright information

© Pleiades Publishing, Inc. 2006