Synthesis of chiral 5-aryltetrahydrofuran-2-ones via yeast bioreduction of γ-keto acids and their esters
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- Mahmoodi, N.O. & Yousefi-Malekroudi, R. Russ J Org Chem (2006) 42: 365. doi:10.1134/S1070428006030043
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Enantioselective reduction of γ-keto acids and related γ-keto esters with Saccharomyces cerevisiae (baker’s yeast) leads to the formation of the corresponding chiral 5-aryltetrahydrofuran-2-ones in satisfactory chemical and optical yields.