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Synthesis of chemical compounds of chitosan with betulin under nearly homogeneous conditions

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Abstract

Chemical compounds of chitosan with betulin have been synthesized with the use of chitosan gels in alcoholic and acetic acid dispersions under nearly homogeneous conditions. The resulting biphilic compounds contain up to one betulin residue per 2–3 chitosan units. The formation of chemical compounds of chitosan with betulin has been confirmed by several physicochemical methods. The procedure developed for the preparation of chitosan gels with alcohol-containing dispersion medium makes it possible to carry out chitosan reactions with compounds poorly soluble in aqueous and acetic acid media.

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Authors and Affiliations

  1. Research Institute of Chemistry, Lobachevskii State University of Nizhny Novgorod, pr. Gagarina 23, Nizhny Novgorod, 603950, Russia

    E. N. Fedoseeva, V. F. Ur’yash, N. Yu. Kokurina & V. B. Fedoseev

  2. Razuvaev Institute of Organometallic Chemistry, Russian Academy of Sciences, ul. Tropinina 49, Nizhny Novgorod, 603137, Russia

    V. B. Fedoseev

Authors
  1. E. N. Fedoseeva
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  2. V. F. Ur’yash
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  3. N. Yu. Kokurina
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  4. V. B. Fedoseev
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Correspondence to E. N. Fedoseeva.

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Original Russian Text © E.N. Fedoseeva, V.F. Ur’yash, N.Yu. Kokurina, V.B. Fedoseev, 2016, published in Zhurnal Obshchei Khimii, 2016, Vol. 86, No. 11, pp. 1893–1900.

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Fedoseeva, E.N., Ur’yash, V.F., Kokurina, N.Y. et al. Synthesis of chemical compounds of chitosan with betulin under nearly homogeneous conditions. Russ J Gen Chem 86, 2534–2540 (2016). https://doi.org/10.1134/S1070363216110219

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  • DOI: https://doi.org/10.1134/S1070363216110219

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