Journal of Analytical Chemistry

, Volume 65, Issue 2, pp 174–182

Gas-chromatographic determination of O-isobutyl-S-2-(N,N-diethylamino)ethyl methylphosphonothioate (VX-like compound) and O-isopropyl methylphosphonofluoridate (Sarin) traces in slag

Authors

  • I. N. Stans’kov
    • Russian Research Institute of Organic Chemistry and Technology
  • V. B. Kondrats’ev
    • Russian Research Institute of Organic Chemistry and Technology
  • E. N. Glukhan
    • Russian Research Institute of Organic Chemistry and Technology
  • V. I. Tsekhmister
    • Russian Research Institute of Organic Chemistry and Technology
  • S. V. Sadovnikov
    • Russian Research Institute of Organic Chemistry and Technology
  • A. P. Suchkov
    • Russian Research Institute of Organic Chemistry and Technology
  • I. D. Derevyagina
    • Russian Research Institute of Organic Chemistry and Technology
Articles

DOI: 10.1134/S1061934810020139

Cite this article as:
Stans’kov, I.N., Kondrats’ev, V.B., Glukhan, E.N. et al. J Anal Chem (2010) 65: 174. doi:10.1134/S1061934810020139

Abstract

Procedures for the determination of 04sobutyl- S-2-(N,N-diethylamino)ethyl methylphosphonothioate (VX-like compound) and sarin traces in slag at levels of 5 × 10-5 and 1 × 10-2 mg/kg, respectively, were developed. The procedures are based on the extraction of organophosphorus chemical warfare agents from slag, the preconcentration of the extract, and the conversion of the analytes into dialkyl methylphos-phonates with the use of optically active alcohols. In this case, a solution of AgNO3 in 4-methyl-2-pentanol or a sodium alcoholate solution was used for the derivatization of VX or sarin, respectively. The resulting dias-tereomers were determined by gas chromatography with the use of a flame-photometric detector. The analysis time was no longer than 1.2 or 1 h for the VX-like compound or sarin, respectively.

Copyright information

© Pleiades Publishing, Ltd. 2010