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A new polymorph of methimazole: Single crystal and powder X-ray diffraction study

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Abstract

A new polymorph of 1-methyl-4-imidazoline-2-thione has been first discovered and studied by X-ray diffraction. The crystal of the new polymorph is monoclinic, the asymmetric part of the cell contains three independent molecules. In the crystal, the key compound is in the form of planar hydrogen-bonded dimers due to the interactions of the N-H…S type. The new modification is of an intensely yellow color in contrast to the previously known colorless forms, is characterized by a lower density but stronger hydrogen bonds; it is formed as a minor impurity to main triclinic polymorph.

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Authors and Affiliations

  1. A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, Moscow, Russia

    O. A. Lodochnikova, A. F. Saifina & I. A. Litvinov

  2. Kazan State Medical University, Kazan, Russia

    A. V. Bodrov & L. E. Nikitina

Authors
  1. O. A. Lodochnikova
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  2. A. V. Bodrov
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  3. A. F. Saifina
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  4. L. E. Nikitina
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  5. I. A. Litvinov
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Correspondence to O. A. Lodochnikova.

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Original Russian Text Copyright © 2013 by O. A. Lodochnikova, A. V. Bodrov, A. F. Saifina, L. E. Nikitina, I. A. Litvinov

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Translated from Zhurnal Strukturnoi Khimii, Vol. 54, No. 1, pp. 146–154, January–February, 2013.

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Lodochnikova, O.A., Bodrov, A.V., Saifina, A.F. et al. A new polymorph of methimazole: Single crystal and powder X-ray diffraction study. J Struct Chem 54, 140–147 (2013). https://doi.org/10.1134/S0022476613010204

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  • DOI: https://doi.org/10.1134/S0022476613010204

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