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Radiation-induced free-radical fragmentation of ceramides in a model system

  • Radiation Chemistry
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Abstract

The radiation-initiated transformations of ceramide as a constituent of micelles were studied. An amide was identified as a ceramide γ-radiolysis product. Determination of other radiolysis products and data on the interaction of the FeSO4-H2O2-ascorbate system with ceramide lead to the conclusion that the amide is formed as a result of OH-induced fragmentation in the polar moiety of the substrate.

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Authors and Affiliations

  1. Research Institute of Physicochemical Problems, Belarussian State University, ul. Leningradskaya 14, Minsk, 220030, Belarus

    I. L. Yurkova

  2. Institute of Medical Physics and Biophysics, Medical Department, Leipzig University, Härtelstrasse 16-18, D-04107, Leipzig, Germany

    J. Arnhold

Authors
  1. I. L. Yurkova
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  2. J. Arnhold
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Correspondence to I. L. Yurkova.

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Original Russian Text © I.L. Yurkova, J. Arnhold, 2009, published in Khimiya Vysokikh Energii, 2009, Vol. 43, No. 4, pp. 320–325.

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Yurkova, I.L., Arnhold, J. Radiation-induced free-radical fragmentation of ceramides in a model system. High Energy Chem 43, 269–273 (2009). https://doi.org/10.1134/S0018143909040043

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  • DOI: https://doi.org/10.1134/S0018143909040043

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