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Formation of composite scaffolds based on chitosan and calcium phosphate

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Abstract

Composite materials based on chitosan and calcium phosphates with the structure and properties close to those of natural human tissues were developed. The possibility of formation of biological apatite, i.e., octacalcium phosphate, was demonstrated. The increase in the strength characteristics was caused by crystallization of the octacalcium phosphate phase on the surface of the material pore space. The materials resemble the extracellular matrix of the body in their structure and composition and can find wide use in the regenerative medicine as a scaffold for osteogenic factors.

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Authors and Affiliations

  1. Baikov Institute of Metallurgy, Russian Academy of Sciences, Leninskii pr. 49, Moscow, 117334, Russia

    A. Yu. Fedotov, S. M. Barinov, V. M. Ievlev, V. P. Sirotinkin & V. S. Komlev

  2. Voronezh State Technical University, Moskovskii pr. 14, Voronezh, 394026, Russia

    S. A. Soldatenko

Authors
  1. A. Yu. Fedotov
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  2. S. M. Barinov
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  3. V. M. Ievlev
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  4. V. P. Sirotinkin
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  5. S. A. Soldatenko
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  6. V. S. Komlev
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Corresponding author

Correspondence to V. S. Komlev.

Additional information

Original Russian Text © A.Yu. Fedotov, S.M. Barinov, V.M. Ievlev, V.P. Sirotinkin, S.A. Soldatenko, V.S. Komlev, 2016, published in Doklady Akademii Nauk, 2016, Vol. 469, No. 1, pp. 54–57.

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Fedotov, A.Y., Barinov, S.M., Ievlev, V.M. et al. Formation of composite scaffolds based on chitosan and calcium phosphate. Dokl Chem 469, 215–218 (2016). https://doi.org/10.1134/S0012500816070016

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  • DOI: https://doi.org/10.1134/S0012500816070016

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