Abstract
When modeling the effects of hypogravity by the method of hindlimb unloading in rats, the area of cross-section in the lumbar part of spinal cord was found to reduce. Analysis of spinal cord slides showed that these changes are associated with a decrease in the area of white substance. The data obtained are consistent with our previous observation of a decrease in expression of the genes encoding myelin proteins. The results of our research give good reasons to believe that myelination failure in CNS is one of the factors that underlie the development of the hypogravity motor syndrome.
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Original Russian Text © O.V. Tyapkina, L.F. Nurullin, P.N. Rezvyakov, I.B. Kozlovskaya, E.E. Nikolsky, R.R. Islamovb, 2012, published in Biofizika, 2012, Vol. 57, No. 5, pp. 876–879.
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Tyapkina, O.V., Nurullin, L.F., Rezvyakov, P.N. et al. Myelination disorders in the mechanism of hypogravity motor syndrome development. BIOPHYSICS 57, 681–683 (2012). https://doi.org/10.1134/S0006350912050223
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DOI: https://doi.org/10.1134/S0006350912050223