Skip to main content
SpringerLink
Log in

Study of a new group of bioregulators isolated from the greater plantain (Plantago major L.)

  • Published:
Applied Biochemistry and Microbiology Aims and scope Submit manuscript

Abstract

Proteins with physicochemical properties and biological activity similar to those of membranotropic homeostatic tissue-specific bioregulators that had been found earlier in various animal tissues were discovered in leaves of the common plantain (Plantago major L.). To study the specific activity of these plant proteins, we developed an experimental model for organotypic roller cultivation of newt (Pleurodeles waltl) skin tissue in vitro. We showed that the plant proteins of interest exert the wound-healing effect, which is characteristic of this plant, on the skin of vertebrates both in vitro and in vivo.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Maznev, N.I., Bol’shaya entsiklopediya zdorov’ya (The Great Encyclopedia of Health), Moscow: AST, 2008.

    Google Scholar 

  2. Yamskova, V.P. and Reznikova, M.M., Zh. Obshch. Biol., 1991, vol. 52, no. 2, pp. 181–191.

    CAS  Google Scholar 

  3. Yamskov, I.A., Yamskova, V.P., Danilenko, A.N., Klemenkova, Z.S., Antipov, B.G., Chernikov, F.R., Gusynina, M.M., and Rybakova, E.Yu., Ros. Khim. Zh. (Zh. Ros. Khim. Obshch. Im. D.I. Mendeleeva), 1999, vol. 43, no. 5, pp. 34–39.

    CAS  Google Scholar 

  4. Krasnov, M.S., Grigoryan, E.N., and Yamskova, V.P., Izv. Akad. Nauk, Ser. Biol., 2003, no. 1, pp. 22–36 [Biol.Bull. (Engl. Transl.), 2003, vol. 30, no. 1, pp. 17–29].

  5. Margasyuk, D.V., Krasnov, M.S., Blagodatskikh, I.V., Grigoryan, E.N., Yamskova, V.P., and Yamskov, I.A., in Biochemical Physics: Frontal Research, Varfolomeev, S.D., Burlakova, E.B., Popov, A.A., and Zaikov, G.E., Eds., Hauppauge: Nova Sci. Publ. Inc., 2007, pp. 49–56.

    Google Scholar 

  6. Krasnov, M.S., Gurmizov, E.P., Yamskova, V.P., and Yamskov, I.A., in Biochemical Physics: Frontal Research, Varfolomeev, S.D., Burlakova, E.B., Popov, A.A., and Zaikov, G.E., Eds., Hauppauge: Nova Sci. Publ. Inc., 2007, pp. 28–37.

    Google Scholar 

  7. Borisenko, A.V., Yamskova, V.P., Krasnov, M.S., Blagodatskikh, I.V., Vecherkin, V.V., and Yamskov, I.A., in Biochemical Physics: Frontal Research, Varfolomeev, S.D., Burlakova, E.B., Popov, A.A., and Zaikov, G.E., Eds., Hauppauge: Nova Sci. Publ. Inc., 2007, pp. 38–48.

    Google Scholar 

  8. Yamskova, V.P., Rybakova, E.Yu., Vecherkin, V.V., Berezin, B.B., Filatova, A.G., Blagodatskikh, I.V., and Yamskov, I.A., in Biochemical Physics: Frontal Research, Varfolomeev, S.D., Burlakova, E.B., Popov, A.A., and Zaikov, G.E., Eds., Hauppauge: Nova Sci. Publ. Inc., 2007, pp. 57–67.

    Google Scholar 

  9. Margasyuk, D.V., Krasnov, M.S., Yamskov, I.A., and Yamskova, V.P., Izv. Akad. Nauk, Ser. Biol., 2008, no. 6, pp. 736–745 [Biol. Bull. (Engl. Transl.), 2008, vol. 35, no. 6, pp. 635–642].

  10. Nazarova, P.A., Krasnov, M.S., Yamskova, V.P., and Yamskov, I.A., Prikl. Biokhim. Mikrobiol., 2006, vol. 42, no. 5, pp. 529–533 [Appl. Biochem. Microbiol. (Engl. Transl.), 2006, vol. 42, no. 5, pp. 464–467].

    PubMed  CAS  Google Scholar 

  11. Yamskova, V.P., Rybakova, E.Yu., Vinogradov, A.A., Vecherkin, V.V., and Yamskov, I.A., Prikl. Biokhim. Mikrobiol., 2004, vol. 40, no. 4, pp. 407–413 [Appl. Biochem. Microbiol. (Engl. Transl.), 2004, vol. 40, no. 4, pp. 345–350].

    Google Scholar 

  12. Yamskova, V.P., Skripnikova, V.S., Molyavka, A.A., Il’ina, A.P., Krasnov, M.S., Margasyuk, D.V., Borisenko, A.V., Berezin, B.B., Kuznetsova, E.S., Buryak, A.K., and Yamskov, I.A., Biokhimiya, 2009, vol. 74, no. 9, pp. 1195–1203 [Biochemistry (Moscow), 2009, vol. 74, no. 9, pp. 971–978].

    Google Scholar 

  13. Dawson, R., Elliott, D., Elliott, W., and Jones, K., Data for Biochemical Research, Oxford: Clarendon, 1986. Translated under the title Spravochnik biokhimika, Moscow: Mir, 1991.

    Google Scholar 

  14. Smith, P.K., Krohn, R.I., Hermanson, G.T., Mallia, A.K., Gartner, F.H., Provenzano, M.D., Fujimoto, E.K., Goeke, N.M., Olson, B.J., and Klenk, D.C., Anal. Biochem., 1985, vol. T. 150, no. 5, pp. C. 76–85.

    Google Scholar 

  15. Laemmli, U.K., Nature, 1970.

  16. Hames, B.D., in Gel Electrophoresis of Proteins. A Practical Approach, Hames, B.D. and Rickwood, D., Eds., Oxford: University Press, 1990.

    Google Scholar 

  17. Engelhardt, N.V., Immunokhimicheskii analiz (Immunochemical Analysis), Moscow: Meditsina, 1968.

    Google Scholar 

  18. Yamskova, V.P., Krasnov, M.S., Margasyuk, D.V., and Yamskov, I.A., Izv. Akad. Nauk, Ser. Biol., 2009, no. 1, pp. 11–17 [Biol. Bull. (Engl. Transl.), 2009, vol. 36, no. 1, pp. 6–11].

  19. Frangioni, G., Borgioli, G., and Bianchi, S., Exp. Zool., 2003, vol. 296A, no. 4, pp. 125–136.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Kol’tsov Institute of Developmental Biology, Russian Academy of Sciences, ul. Vavilova 26, Moscow, 119334, Russia

    M. S. Krasnov, V. P. Yamskova & E. Yu. Rybakova

  2. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, ul. Vavilova 28, Moscow, 119991, Russia

    D. V. Margasyuk, O. G. Kulikova, A. P. Il’ina & I. A. Yamskov

Authors
  1. M. S. Krasnov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. V. P. Yamskova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D. V. Margasyuk
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. O. G. Kulikova
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. A. P. Il’ina
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. E. Yu. Rybakova
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. I. A. Yamskov
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to M. S. Krasnov.

Additional information

Original Russian Text © M.S. Krasnov, V.P. Yamskova, D.V. Margasyuk, O.G. Kulikova, A.P. Il’ina, E.Yu. Rybakova, I.A. Yamskov, 2011, published in Prikladnaya Biokhimiya i Mikrobiologiya, 2011, Vol. 47, No. 2, pp. 146–153.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Krasnov, M.S., Yamskova, V.P., Margasyuk, D.V. et al. Study of a new group of bioregulators isolated from the greater plantain (Plantago major L.). Appl Biochem Microbiol 47, 128–135 (2011). https://doi.org/10.1134/S0003683811020086

Download citation

  • Received:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1134/S0003683811020086

Keywords

Search

Navigation